Interactor 1: GPC1 (P35052)
Glypican-1 [Cleaved into: Secreted glypican-1]
Gene: GPC1

Interactor 2: PTEN (P60484)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)
Gene: PTEN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.60 0.595

The method score is based on:

Property Details
Experiments 26561776, 30631154
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005576 - extracellular region
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0016477 - cell migration
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 558
Hs

1 403
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024