HitPredict

Interactor 1: UBC2 (P35129)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Lethal protein 70) (Ubiquitin carrier protein 2) (Ubiquitin-protein ligase 2)
Gene: let-70

Interactor 2: Q19214 (Q19214)
RING-type domain-containing protein
Gene: CELE_F08G12.5

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	15530417
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Ce			1 185
+	Hs
		1377469 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI17_HUMAN (25-176): 1.48e-35: 131: 17.76
+	Hs
		1336390 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI39_HUMAN (31-176): 2.25e-34: 128: 20.55
+	Hs
		1354526 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI10_HUMAN (25-172): 8.79e-33: 123: 14.87
+	Hs
		175730 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI18_HUMAN (37-152): 7.52e-32: 122: 25.98
+	Hs
		1318719 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRIM5_HUMAN (27-176): 5.85e-32: 121: 18.00
+	Hs
		175653 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		TRI18_HUMAN (37-152): 7.52e-32: 122: 25.98
+	Hs
		537142 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI27_HUMAN (25-173): 1.72e-31: 120: 16.78
+	Hs
		1318532 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI31_HUMAN (25-176): 4.94e-31: 118: 20.40
+	Hs
		1285831 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI43_HUMAN (27-176): 1.49e-30: 117: 19.33
+	Hs
		1151762 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		Q6GX22_HUMAN (37-152): 8.98e-30: 116: 25.98
+	Hs
		1356055 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRIM1_HUMAN (37-152): 6.56e-30: 116: 25.98
+	Hs
		135045 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI38_HUMAN (25-169): 4.6e-28: 110: 17.93
+	Hs
		1357712 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI35_HUMAN (21-170): 1.8e-27: 109: 18.67
+	Hs
		262201 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRIM3_HUMAN (20-176): 3.4e-27: 109: 14.71
+	Hs
		135012 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		TRI38_HUMAN (25-169): 4.6e-28: 110: 17.93
+	Hs
		262161 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		TRIM3_HUMAN (20-176): 3.4e-27: 109: 14.71
+	Hs
		1317493 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI54_HUMAN (35-159): 5.1e-27: 106: 21.17
+	Hs
		1318358 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRIM8_HUMAN (36-119): 4.2e-11: 62.4: 28.24
+	Hs
		1052807 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI25_HUMAN (28-147): 1.32e-10: 61.3: 24.00
+	Hs
		1313765 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI62_HUMAN (36-157): 1.18e-10: 61.3: 22.38