HitPredict

Interactor 1: UBC2 (P35129)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Lethal protein 70) (Ubiquitin carrier protein 2) (Ubiquitin-protein ligase 2)
Gene: let-70

Interactor 2: Q20369 (Q20369)
RING-type domain-containing protein
Gene: CELE_F43G6.8

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	15530417
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Ce			1 263
+	Hs
		282581 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		RNF8_HUMAN (39-257): 2.63e-41: 149: 17.62
+	Hs
		282607 UB2D2_HUMAN (1-147): 5.79e-82: 239: 93.88		RNF8_HUMAN (39-257): 2.63e-41: 149: 17.62
+	Hs
		849346 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		NHLC1_HUMAN (176-263): 6.98e-25: 103: 22.22
+	Ce
		715104 UBC2_CAEEL (1-147): 4.45e-82: 239: 100.00		NHL1_CAEEL (159-260): 6e-24: 102: 19.81
+	Hs
		262201 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRIM3_HUMAN (178-263): 2.03e-22: 98: 25.56
+	Hs
		1318738 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRIM2_HUMAN (178-263): 2.89e-22: 97.6: 24.44
+	Hs
		262161 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		TRIM3_HUMAN (178-263): 2.03e-22: 98: 25.56
+	Hs
		849440 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		TRIM2_HUMAN (178-263): 2.89e-22: 97.6: 24.44
+	Hs
		262167 UB2D2_HUMAN (1-147): 5.79e-82: 239: 93.88		TRIM3_HUMAN (178-263): 2.03e-22: 98: 25.56
+	Hs
		849352 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		SH3R1_HUMAN (188-263): 1.69e-21: 95.3: 25.97
+	Hs
		734819 UB2D4_HUMAN (1-147): 3.06e-83: 242: 92.52		TRI23_HUMAN (195-263): 1.79e-20: 92.2: 38.89
+	At
		715133 UBC9_ARATH (1-147): 7.05e-82: 239: 78.23		Q84JZ7_ARATH (173-263): 2.42e-22: 94.6: 24.30
+	Hs
		849316 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		TRI32_HUMAN (191-263): 7.1e-21: 93.4: 33.33
+	Hs
		919715 UB2D2_HUMAN (1-147): 5.79e-82: 239: 93.88		TRI32_HUMAN (191-263): 7.1e-21: 93.4: 33.33
+	Hs
		734563 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		TRI23_HUMAN (195-263): 1.79e-20: 92.2: 38.89
+	Hs
		734581 UB2D2_HUMAN (1-147): 5.79e-82: 239: 93.88		TRI23_HUMAN (195-263): 1.79e-20: 92.2: 38.89
+	Hs
		849370 UB2D1_HUMAN (1-147): 2.25e-82: 240: 89.12		RN182_HUMAN (182-263): 2.92e-20: 88.8: 24.44
+	Hs
		242838 UB2D2_HUMAN (1-147): 5.79e-82: 239: 93.88		TRI13_HUMAN (197-260): 1.74e-18: 86: 30.14
+	At
		715122 UBC8_ARATH (1-147): 2.46e-82: 240: 79.59		KEG_ARATH (199-263): 8.19e-18: 84.8: 30.44
+	Ce
		283756 UBC2_CAEEL (1-147): 4.45e-82: 239: 100.00		O76354_CAEEL (195-263): 1.03e-10: 63.6: 30.67