HitPredict

Interactor 1: AP1S1 (P35181)
AP-1 complex subunit sigma-1 (Clathrin assembly protein complex 1 sigma-1 small chain) (Clathrin coat assembly protein AP19) (Clathrin coat-associated protein AP19) (Golgi adaptor AP-1 19 kDa adaptin) (HA1 19 kDa subunit) (Sigma1-adaptin)
Gene: APS1

Interactor 2: AP1B1 (P36000)
AP-1 complex subunit beta-1 (Beta-1-adaptin) (Clathrin assembly protein complex 1 beta-1 large chain) (Clathrin assembly protein large beta-1 chain)
Gene: APL2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.967

The method score is based on:

Property Details
Experiments 10564262, 11805826, 16554755, 16429126, 22940862, 23056294, 37968396
Identification Methods coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Adaptin_N~Clat_adaptor_s
Common GO terms GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0006896 - Golgi to vacuole transport
GO:0016192 - vesicle-mediated transport
GO:0030121 - AP-1 adaptor complex
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 156
Sc

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024