Protein: S39A1
Zinc transporter ZIP1 (Solute carrier family 39 member 1) (Zinc-iron-regulated transporter-like) (Zrt- and Irt-like protein 1) (ZIP-1) (hZIP1)

Gene: S39A1, SLC39A1
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q9NY26

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0005102 - signaling receptor binding
GO:0005385 - zinc ion transmembrane transporter activity
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

845487

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

8

High-throughput

0.667

High

702860

5HT2C
5-hydroxytryptamine receptor 2C

2

9

High-throughput

0.633

High

622693

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

10

High-throughput

0.628

High

835411

VIPR2
Vasoactive intestinal polypeptide receptor 2

2

11

High-throughput

0.628

High

1159120

C3AR
C3a anaphylatoxin chemotactic receptor

2

14

High-throughput

0.628

High

1231151

SCAR3
Scavenger receptor class A member 3

2

1

High-throughput

0.611

High

1431468

P2Y12
P2Y purinoceptor 12

2

18

High-throughput

0.611

High

642303

COMT
Catechol O-methyltransferase

2

8

High-throughput

0.606

High

883448

CY561
Transmembrane ascorbate-dependent reductase CYB561

2

1

High-throughput

0.606

High

1388811

YIPF6
Protein YIPF6

2

1

High-throughput

0.553

High

1116397

5HT4R
5-hydroxytryptamine receptor 4

1

9

High-throughput

0.541

High

640479

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

12

High-throughput

0.536

High

669078

FPR2
N-formyl peptide receptor 2

1

19

High-throughput

0.536

High

722646

CTR1
High affinity cationic amino acid transporter 1

1

3

High-throughput

0.536

High

1316387

AGRG5
Adhesion G-protein coupled receptor G5

1

11

High-throughput

0.536

High

1350090

SPP2B
Signal peptide peptidase-like 2B

1

6

High-throughput

0.536

High

1452204

CLC2D
C-type lectin domain family 2 member D

1

7

High-throughput

0.536

High

1452206

FZD10
Frizzled-10

1

5

High-throughput

0.536

High

63706

A5PKU2
TUSC5 protein

1

1

High-throughput

0.515

High

1432042

TMM60
Transmembrane protein 60

1

1

High-throughput

0.515

High

596539

CTLA4
Cytotoxic T-lymphocyte protein 4

1

0

High-throughput

0.513

High

1452207

NOTC3
Neurogenic locus notch homolog protein 3

1

4

Small-scale

0.501

High

939541

FCGRN
IgG receptor FcRn large subunit p51

1

14

High-throughput

0.489

High

1312135

TARG1
Trafficking regulator of GLUT4 1

1

1

High-throughput

0.481

High

1391308

CERS2
Ceramide synthase 2

1

8

High-throughput

0.481

High

218857

TGON2
Trans-Golgi network integral membrane protein 2

1

8

High-throughput

0.479

High

1366275

LPAR1
Lysophosphatidic acid receptor 1

1

20

High-throughput

0.479

High

1418475

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.479

High

1386609

OPTN
Optineurin

1

12

High-throughput

0.470

High

1431628

CXL16
C-X-C motif chemokine 16

1

0

High-throughput

0.460

High

178422

NPC1
NPC intracellular cholesterol transporter 1

1

0

High-throughput

0.458

High

1429575

LSG1
Large subunit GTPase 1 homolog

1

0

High-throughput

0.458

High

363932

EGFR
Epidermal growth factor receptor

1

16

High-throughput

0.445

High

417805

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.445

High

423322

A4
Amyloid-beta precursor protein

1

12

High-throughput

0.445

High

469216

SRPRA
Signal recognition particle receptor subunit alpha

1

7

High-throughput

0.445

High

648317

ENPP1
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1

1

9

High-throughput

0.445

High

1083086

MGAT2
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

1

5

High-throughput

0.445

High

1091993

SEC20
Vesicle transport protein SEC20

1

2

High-throughput

0.445

High

1126280

GALT3
Polypeptide N-acetylgalactosaminyltransferase 3

1

20

High-throughput

0.445

High

1246027

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

4

High-throughput

0.445

High

1286308

GALT7
N-acetylgalactosaminyltransferase 7

1

20

High-throughput

0.445

High

1310700

TRI59
Tripartite motif-containing protein 59

1

1

High-throughput

0.445

High

1316596

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

1

High-throughput

0.445

High

1348343

GOGA5
Golgin subfamily A member 5

1

15

High-throughput

0.445

High

1358379

SCFD1
Sec1 family domain-containing protein 1

1

6

High-throughput

0.445

High

1407378

TM9S2
Transmembrane 9 superfamily member 2

1

4

High-throughput

0.445

High

1452203

STX18
Syntaxin-18

1

1

High-throughput

0.445

High

1270344

SPT6H
Transcription elongation factor SPT6

1

4

High-throughput

0.437

High

300051

CBPD
Carboxypeptidase D

1

0

High-throughput

0.426

High

863573

STT3A
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

1

0

High-throughput

0.426

High

1311293

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

0

High-throughput

0.426

High

1449573

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.426

High

1452205

PRAF1
Prenylated Rab acceptor protein 1

1

0

High-throughput

0.426

High

1347564

SMRC2
SWI/SNF complex subunit SMARCC2

1

1

High-throughput

0.407

High

1395219

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

1

High-throughput

0.407

High

1432549

SNX25
Sorting nexin-25

1

8

High-throughput

0.407

High

1059107

CXCL9
C-X-C motif chemokine 9

2

0

High-throughput

0.316

High

248250

NDK8
Putative nucleoside diphosphate kinase

2

0

High-throughput

0.298

High

1382463

SYAP1
Synapse-associated protein 1

1

0

High-throughput

0.279

Low

250348

VINEX
Vinexin

1

0

High-throughput

0.269

Low

1310004

PKHM2
Pleckstrin homology domain-containing family M member 2

1

0

High-throughput

0.238

Low

1287999

PB1
Protein polybromo-1

1

0

High-throughput

0.232

Low

1393292

FMC1
Protein FMC1 homolog

1

0

High-throughput

0.232

Low

1451991

TEX10
Testis-expressed protein 10

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025