HitPredict

Interactor 1: B3DN64 (B3DN64)
Guanine nucleotide exchange factor in mesoderm, isoform G (LP15490p)
Gene: GEFmeso

Interactor 2: CDC42 (P40793)
Cdc42 homolog (EC 3.6.5.2)
Gene: CDC42

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.80	0.687

Property	Details
Experiments	16581976, 25753922
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	Ras~RhoGEF
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1237 Dm			1 191
+	Dm
		71592 B3DN64_DROME (1-1237): 0: 1118: 100.00		RAC1_DROME (1-191): 3.34e-79: 235: 69.79
+	Dm
		776895 Q8MSP7_DROME (1-1237): 0: 1113: 99.36		RAC1_DROME (1-191): 3.34e-79: 235: 69.79
+	Hs
		564524 ARHG7_HUMAN (21-744): 4.36e-116: 382: 15.35		RHOQ_HUMAN (4-187): 1.25e-92: 270: 69.57
+	Hs
		564535 ARHG6_HUMAN (21-788): 1.21e-114: 378: 15.72		RHOQ_HUMAN (4-187): 1.25e-92: 270: 69.57
+	Hs
		1049733 ARHG7_HUMAN (21-744): 4.36e-116: 382: 15.35		RHOJ_HUMAN (2-188): 8.84e-84: 248: 63.64
+	Hs
		1066050 ARHG6_HUMAN (21-788): 1.21e-114: 378: 15.72		RHOJ_HUMAN (2-188): 8.84e-84: 248: 63.64
+	Hs
		925271 ARHG7_HUMAN (21-744): 4.36e-116: 382: 15.35		RAC1_HUMAN (1-191): 1.8e-81: 241: 69.63
+	Hs
		855782 VAV2_HUMAN (20-747): 8.53e-115: 381: 14.01		RAC1_HUMAN (1-191): 1.8e-81: 241: 69.63
+	Hs
		925289 ARHG6_HUMAN (21-788): 1.21e-114: 378: 15.72		RAC1_HUMAN (1-191): 1.8e-81: 241: 69.63
+	Hs
		893997 ARHG7_HUMAN (21-744): 4.36e-116: 382: 15.35		CDC42_HUMAN (1-191): 6.36e-79: 235: 92.67
+	Hs
		545368 ARHG7_HUMAN (21-744): 4.36e-116: 382: 15.35		RAC2_HUMAN (1-191): 1.28e-78: 234: 68.75
+	Hs
		855778 VAV2_HUMAN (20-747): 8.53e-115: 381: 14.01		CDC42_HUMAN (1-191): 6.36e-79: 235: 92.67
+	Hs
		894026 ARHG6_HUMAN (21-788): 1.21e-114: 378: 15.72		CDC42_HUMAN (1-191): 6.36e-79: 235: 92.67
+	Hs
		545388 ARHG6_HUMAN (21-788): 1.21e-114: 378: 15.72		RAC2_HUMAN (1-191): 1.28e-78: 234: 68.75
+	Hs
		855779 VAV2_HUMAN (20-747): 8.53e-115: 381: 14.01		RHOA_HUMAN (5-191): 1.22e-77: 231: 52.41
+	Hs
		892365 ARHG7_HUMAN (21-744): 4.36e-116: 382: 15.35		RAC3_HUMAN (1-177): 2.67e-76: 228: 71.75
+	Hs
		900768 ARHG2_HUMAN (104-923): 7.46e-112: 376: 13.67		RHOA_HUMAN (5-191): 1.22e-77: 231: 52.41
+	Hs
		892381 ARHG6_HUMAN (21-788): 1.21e-114: 378: 15.72		RAC3_HUMAN (1-177): 2.67e-76: 228: 71.75
+	Hs
		1049714 ARHG7_HUMAN (21-744): 4.36e-116: 382: 15.35		RHOU_HUMAN (4-187): 4.19e-71: 217: 57.61
+	Hs
		1066032 ARHG6_HUMAN (21-788): 1.21e-114: 378: 15.72		RHOU_HUMAN (4-187): 4.19e-71: 217: 57.61