Protein: RUXG
Small nuclear ribonucleoprotein G (snRNP-G) (Sm protein G) (Sm-G) (SmG)

Gene: RUXG, SNRPG
Organism: Homo sapiens
Interactions: 179
UniProt ID: P62308

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

973679

RUXE
Small nuclear ribonucleoprotein E

10

20

Small-scale

0.973

High

926160

ICLN
Methylosome subunit pICln

6

11

Small-scale

0.958

High

974110

SMD3
Small nuclear ribonucleoprotein Sm D3

4

20

Small-scale

0.894

High

472590

RU17
U1 small nuclear ribonucleoprotein 70 kDa

4

20

Small-scale

0.890

High

974109

SMD2
Small nuclear ribonucleoprotein Sm D2

4

20

High-throughput

0.886

High

974130

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

4

16

High-throughput

0.886

High

973869

RUXF
Small nuclear ribonucleoprotein F

3

20

High-throughput

0.858

High

480079

RU1C
U1 small nuclear ribonucleoprotein C

3

9

High-throughput

0.847

High

485601

RU2A
U2 small nuclear ribonucleoprotein A'

3

14

High-throughput

0.847

High

574202

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

3

19

High-throughput

0.847

High

974146

PRP8
Pre-mRNA-processing-splicing factor 8

3

10

High-throughput

0.847

High

167076

GEMI2
Gem-associated protein 2

3

9

Small-scale

0.839

High

974106

LSM3
U6 snRNA-associated Sm-like protein LSm3

2

20

High-throughput

0.806

High

215064

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

2

11

High-throughput

0.789

High

974108

SMD1
Small nuclear ribonucleoprotein Sm D1

2

20

High-throughput

0.789

High

974112

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

19

High-throughput

0.789

High

974120

SF3A3
Splicing factor 3A subunit 3

2

7

High-throughput

0.789

High

974129

SART3
Spliceosome associated factor 3, U4/U6 recycling protein

2

20

High-throughput

0.789

High

974175

LSM10
U7 snRNA-associated Sm-like protein LSm10

2

20

High-throughput

0.789

High

974200

PKRI1
PRKR-interacting protein 1

2

4

High-throughput

0.789

High

974213

ZMAT5
Zinc finger matrin-type protein 5

2

3

High-throughput

0.789

High

974139

SMN
Survival motor neuron protein

6

13

Small-scale

0.736

High

974107

LSM6
U6 snRNA-associated Sm-like protein LSm6

1

20

High-throughput

0.691

High

974150

MEPCE
7SK snRNA methylphosphate capping enzyme

4

10

High-throughput

0.686

High

974127

FHL3
Four and a half LIM domains protein 3

3

1

High-throughput

0.675

High

974215

DDX20
Probable ATP-dependent RNA helicase DDX20

3

20

Small-scale

0.674

High

974169

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

3

10

High-throughput

0.667

High

974177

DDT4L
DNA damage-inducible transcript 4-like protein

5

1

High-throughput

0.663

High

335806

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

3

6

High-throughput

0.662

High

974166

GEMI5
Gem-associated protein 5

3

6

Small-scale

0.660

High

974170

GEMI6
Gem-associated protein 6

3

6

Small-scale

0.660

High

974122

SF3B2
Splicing factor 3B subunit 2

3

7

High-throughput

0.656

High

974134

SF3A2
Splicing factor 3A subunit 2

3

8

Small-scale

0.656

High

974191

DDX23
Probable ATP-dependent RNA helicase DDX23

3

16

High-throughput

0.656

High

281026

TACC1
Transforming acidic coiled-coil-containing protein 1

2

5

Small-scale

0.647

High

178010

LSM1
U6 snRNA-associated Sm-like protein LSm1

1

19

High-throughput

0.618

High

974222

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

20

High-throughput

0.618

High

209235

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

2

20

High-throughput

0.611

High

212193

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

2

6

High-throughput

0.611

High

225271

HTSF1
17S U2 SnRNP complex component HTATSF1

2

16

High-throughput

0.611

High

245083

AQR
RNA helicase aquarius

2

11

High-throughput

0.611

High

250985

PRP17
Pre-mRNA-processing factor 17

2

20

High-throughput

0.611

High

285855

SF3B1
Splicing factor 3B subunit 1

2

9

High-throughput

0.611

High

289490

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

2

20

High-throughput

0.611

High

321484

PRP6
Pre-mRNA-processing factor 6

2

20

High-throughput

0.611

High

351319

SYF2
Pre-mRNA-splicing factor SYF2

2

5

High-throughput

0.611

High

471806

RU2B
U2 small nuclear ribonucleoprotein B''

2

20

High-throughput

0.611

High

477978

SNRPA
U1 small nuclear ribonucleoprotein A

2

20

High-throughput

0.611

High

944446

GEMI4
Gem-associated protein 4

2

5

High-throughput

0.611

High

974114

LSM11
U7 snRNA-associated Sm-like protein LSm11

2

5

High-throughput

0.611

High

974115

TXN4A
Thioredoxin-like protein 4A

2

8

High-throughput

0.611

High

974123

SNW1
SNW domain-containing protein 1

2

5

High-throughput

0.611

High

974133

SF3B4
Splicing factor 3B subunit 4

2

13

High-throughput

0.611

High

974135

SF3A1
Splicing factor 3A subunit 1

2

10

High-throughput

0.611

High

974137

U2AFM
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2

2

4

High-throughput

0.611

High

974138

U1SBP
U11/U12 small nuclear ribonucleoprotein 35 kDa protein

2

18

High-throughput

0.611

High

974140

C19L2
CWF19-like protein 2

2

6

High-throughput

0.611

High

974145

SNR48
U11/U12 small nuclear ribonucleoprotein 48 kDa protein

2

4

High-throughput

0.611

High

974153

CATAC
Centrosomal AT-AC splicing factor

2

3

High-throughput

0.611

High

974158

CMTR2
Cap-specific mRNA

2

4

High-throughput

0.611

High

974161

PDCD7
Programmed cell death protein 7

2

4

High-throughput

0.611

High

974167

CCD12
Coiled-coil domain-containing protein 12

2

4

High-throughput

0.611

High

974168

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

3

High-throughput

0.611

High

974178

ESS2
Splicing factor ESS-2 homolog

2

2

High-throughput

0.611

High

974181

TOE1
Target of EGR1 protein 1

2

4

High-throughput

0.611

High

974184

RNPC3
RNA-binding region-containing protein 3

2

20

High-throughput

0.611

High

974185

TGS1
Trimethylguanosine synthase

2

4

High-throughput

0.611

High

974188

GPTC1
G patch domain-containing protein 1

2

6

High-throughput

0.611

High

974189

WDR83
WD repeat domain-containing protein 83

2

20

High-throughput

0.611

High

974193

NADAP
Kanadaptin

2

8

High-throughput

0.611

High

974194

CRNL1
Crooked neck-like protein 1

2

20

High-throughput

0.611

High

974197

DHX35
Probable ATP-dependent RNA helicase DHX35

2

16

High-throughput

0.611

High

974198

STPAP
Speckle targeted PIP5K1A-regulated poly(A) polymerase

2

6

High-throughput

0.611

High

974203

SYF1
Pre-mRNA-splicing factor SYF1

2

20

High-throughput

0.611

High

974207

GEMI8
Gem-associated protein 8

2

6

High-throughput

0.611

High

974211

TFP11
Tuftelin-interacting protein 11

2

14

High-throughput

0.611

High

974220

PPIE
Peptidyl-prolyl cis-trans isomerase E

2

8

High-throughput

0.611

High

974223

SF3B6
Splicing factor 3B subunit 6

2

20

High-throughput

0.611

High

974224

PAXB1
PAX3- and PAX7-binding protein 1

2

5

High-throughput

0.611

High

974225

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

2

4

High-throughput

0.611

High

766397

PHB1
Prohibitin 1

2

2

High-throughput

0.584

High

974160

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

2

12

Small-scale

0.584

High

974208

AKA7G
A-kinase anchor protein 7 isoform gamma

2

12

High-throughput

0.584

High

395829

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

440475

FYN
Tyrosine-protein kinase Fyn

2

2

High-throughput

0.571

High

974113

H31
Histone H3.1

2

0

High-throughput

0.559

High

974162

GPT11
G patch domain-containing protein 11

2

4

High-throughput

0.558

High

352624

TCL1B
T-cell leukemia/lymphoma protein 1B

2

2

High-throughput

0.553

High

974117

TLE1
Transducin-like enhancer protein 1

1

19

High-throughput

0.541

High

162528

ANM5
Protein arginine N-methyltransferase 5

1

8

High-throughput

0.536

High

175637

SR140
U2 snRNP-associated SURP motif-containing protein

1

8

High-throughput

0.536

High

326821

SPN1
Snurportin-1

1

4

High-throughput

0.536

High

974124

CUL1
Cullin-1

1

13

High-throughput

0.536

High

974125

CUL3
Cullin-3

1

13

High-throughput

0.536

High

974126

CUL4B
Cullin-4B

1

13

High-throughput

0.536

High

974142

EAPP
E2F-associated phosphoprotein

1

3

High-throughput

0.536

High

974144

C19L1
CWF19-like protein 1

1

8

High-throughput

0.536

High

974152

PHF5A
PHD finger-like domain-containing protein 5A

1

3

High-throughput

0.536

High

974154

ZCH18
Zinc finger CCCH domain-containing protein 18

1

9

High-throughput

0.536

High

974155

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

7

High-throughput

0.536

High

974156

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

15

High-throughput

0.536

High

974164

ZCRB1
Zinc finger CCHC-type and RNA-binding motif-containing protein 1

1

14

High-throughput

0.536

High

974171

CSN5
COP9 signalosome complex subunit 5

1

3

High-throughput

0.536

High

974172

CUL5
Cullin-5

1

13

High-throughput

0.536

High

974180

DCNL1
DCN1-like protein 1

1

1

High-throughput

0.536

High

974182

SPF45
Splicing factor 45

1

13

High-throughput

0.536

High

974186

CDC5L
Cell division cycle 5-like protein

1

8

High-throughput

0.536

High

974192

SF3B5
Splicing factor 3B subunit 5

1

6

High-throughput

0.536

High

974199

GEMI7
Gem-associated protein 7

1

1

High-throughput

0.536

High

974209

KLHL8
Kelch-like protein 8

1

4

High-throughput

0.536

High

974221

AAR2
Protein AAR2 homolog

1

5

High-throughput

0.536

High

974128

DPYL1
Dihydropyrimidinase-related protein 1

1

0

High-throughput

0.518

High

974151

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.518

High

974201

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.513

High

974204

MED4
Mediator of RNA polymerase II transcription subunit 4

1

0

High-throughput

0.513

High

974218

MED23
Mediator of RNA polymerase II transcription subunit 23

1

0

High-throughput

0.513

High

974216

ERG28
Ergosterol biosynthetic protein 28 homolog

1

1

High-throughput

0.494

High

974118

GABP1
GA-binding protein subunit beta-1

1

0

High-throughput

0.493

High

974163

NF2IP
NFATC2-interacting protein

1

0

High-throughput

0.493

High

974173

RBPMS
RNA-binding protein with multiple splicing

1

2

High-throughput

0.481

High

128928

MEN1
Menin

1

1

High-throughput

0.479

High

241303

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

259737

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

335063

ARI2
E3 ubiquitin-protein ligase ARIH2

1

5

High-throughput

0.479

High

371664

MYC
Myc proto-oncogene protein

1

14

High-throughput

0.479

High

375359

RASK
GTPase KRas

1

2

High-throughput

0.479

High

405994

MYCN
N-myc proto-oncogene protein

1

13

High-throughput

0.479

High

429657

JUN
Transcription factor Jun

1

4

High-throughput

0.479

High

541924

TOP1
DNA topoisomerase 1

1

4

High-throughput

0.479

High

606559

CEBPB
CCAAT/enhancer-binding protein beta

1

5

High-throughput

0.479

High

620260

NUCL
Nucleolin

1

6

High-throughput

0.479

High

684964

DNMT1
DNA

1

1

Small-scale

0.479

High

851492

GATA4
Transcription factor GATA-4

1

2

High-throughput

0.479

High

904545

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.479

High

937691

FOXA1
Hepatocyte nuclear factor 3-alpha

1

1

High-throughput

0.479

High

961926

RHOA
Transforming protein RhoA

1

10

High-throughput

0.479

High

970245

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

974111

H4
Histone H4

1

4

High-throughput

0.479

High

974119

FOXO1
Forkhead box protein O1

1

2

High-throughput

0.479

High

974121

NFX1
Transcriptional repressor NF-X1

1

1

High-throughput

0.479

High

974132

RNPS1
RNA-binding protein with serine-rich domain 1

1

20

High-throughput

0.479

High

974141

LARP7
La-related protein 7

1

14

High-throughput

0.479

High

974143

RC3H1
Roquin-1

1

2

High-throughput

0.479

High

974148

LN28B
Protein lin-28 homolog B

1

8

High-throughput

0.479

High

974157

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

974165

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

1

High-throughput

0.479

High

974176

S7A6O
Probable RNA polymerase II nuclear localization protein SLC7A6OS

1

1

High-throughput

0.479

High

974179

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

9

High-throughput

0.479

High

974183

RSRC1
Serine/Arginine-related protein 53

1

3

High-throughput

0.479

High

974187

TBX5
T-box transcription factor TBX5

1

1

High-throughput

0.479

High

974190

RBM42
RNA-binding protein 42

1

15

High-throughput

0.479

High

974202

LN28A
Protein lin-28 homolog A

1

8

High-throughput

0.479

High

974206

RBM22
Pre-mRNA-splicing factor RBM22

1

17

High-throughput

0.479

High

974212

DUX4
Double homeobox protein 4

1

3

High-throughput

0.479

High

974214

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

974217

ZN346
Zinc finger protein 346

1

1

High-throughput

0.479

High

974219

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

6

High-throughput

0.479

High

974131

PEA15
Astrocytic phosphoprotein PEA-15

1

0

Small-scale

0.460

High

629729

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

784576

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

0

High-throughput

0.458

High

818828

TYRP2
L-dopachrome tautomerase

1

0

High-throughput

0.458

High

833047

EIF2D
Eukaryotic translation initiation factor 2D

1

0

High-throughput

0.458

High

974147

KAT3
Kynurenine--oxoglutarate transaminase 3

1

0

High-throughput

0.458

High

974174

SBP2L
Selenocysteine insertion sequence-binding protein 2-like

1

0

High-throughput

0.458

High

974205

SYFB
Phenylalanine--tRNA ligase beta subunit

1

0

High-throughput

0.458

High

327908

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

8

High-throughput

0.445

High

529524

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.445

High

952064

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

8

High-throughput

0.445

High

974136

SF01
Splicing factor 1

1

4

High-throughput

0.445

High

974195

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

8

High-throughput

0.445

High

974196

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

8

High-throughput

0.445

High

974149

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

886714

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.408

High

224415

AKA7A
A-kinase anchor protein 7 isoforms alpha and beta

1

12

High-throughput

0.407

High

248390

GDF9
Growth/differentiation factor 9

1

0

High-throughput

0.282

High

974210

CE126
Centrosomal protein of 126 kDa

1

0

High-throughput

0.282

High

51316

NTM2F
NUT family member 2F

1

0

High-throughput

0.279

Low

974116

TFF2
Trefoil factor 2

1

0

High-throughput

0.268

Low

974159

ABRA
Actin-binding Rho-activating protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025