Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: RUNX3 (Q13761)
Runt-related transcription factor 3 (Acute myeloid leukemia 2 protein) (Core-binding factor subunit alpha-3) (CBF-alpha-3) (Oncogene AML-2) (Polyomavirus enhancer-binding protein 2 alpha C subunit) (PEA2-alpha C) (PEBP2-alpha C) (SL3-3 enhancer factor 1 alpha C subunit) (SL3/AKV core-binding factor alpha C subunit)
Gene: RUNX3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.53 0.60 0.565

The method score is based on:

Property Details
Experiments 18772112
Identification Methods anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, pull down, chromatin immunoprecipitation assay
Interaction Type association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001222 - transcription corepressor binding
GO:0002062 - chondrocyte differentiation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 781
Hs

1 415
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024