HitPredict

Interactor 1: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Interactor 2: PTN14 (Q15678)
Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez)
Gene: PTPN14

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12808048
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0008285 - negative regulation of cell population proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 781 Hs			1 1187
+	Rn
		88715 CTNB1_RAT (1-781): 0: 625: 99.74		D3ZSL5_RAT (340-1187): 0: 638: 91.08
+	Hs
		616904 CTNB1_HUMAN (1-781): 0: 626: 100.00		PTPRB_HUMAN (597-1186): 2.37e-136: 459: 22.78
+	Hs
		576992 CTNB1_HUMAN (1-781): 0: 626: 100.00		PTPRA_HUMAN (428-1181): 5.96e-139: 442: 18.42
+	Rn
		1145481 CTNB1_RAT (1-781): 0: 625: 99.74		PTPRF_RAT (364-1179): 6.42e-119: 408: 16.26
+	Mm
		56908 CTNB1_MOUSE (1-781): 0: 624: 99.87		PTPRF_MOUSE (364-1179): 9.84e-118: 405: 16.01
+	Hs
		489914 CTNB1_HUMAN (1-781): 0: 626: 100.00		PTPRF_HUMAN (364-1179): 1.6e-116: 401: 15.88
+	Hs
		717036 CTNB1_HUMAN (1-781): 0: 626: 100.00		PTPRJ_HUMAN (868-1185): 1.34e-115: 392: 29.25
+	Hs
		546951 CTNB1_HUMAN (1-781): 0: 626: 100.00		EZRI_HUMAN (18-364): 4.84e-121: 387: 20.96
+	Hs
		717361 CTNB1_HUMAN (1-781): 0: 626: 100.00		E41L5_HUMAN (17-319): 2.76e-117: 382: 27.33
+	Hs
		573593 CTNB1_HUMAN (1-781): 0: 626: 100.00		PTN1_HUMAN (891-1179): 1.76e-118: 375: 31.85
+	Hs
		717037 CTNB1_HUMAN (1-781): 0: 626: 100.00		PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36
+	Mm
		660881 CTNB1_MOUSE (1-781): 0: 624: 99.87		PTPRM_MOUSE (563-1183): 3.21e-71: 263: 14.75
+	Hs
		717099 CTNB1_HUMAN (1-781): 0: 626: 100.00		PTPRK_HUMAN (561-1184): 9.67e-69: 255: 14.87
+	Hs
		489895 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		PTPRF_HUMAN (364-1179): 1.6e-116: 401: 15.88
+	Dm
		578785 ARM_DROME (1-780): 9.15e-160: 486: 64.49		Q9W0R3_DROME (616-1185): 9.09e-119: 393: 20.64
+	Hs
		542300 PLAK_HUMAN (8-752): 2.69e-158: 479: 67.42		PTPRJ_HUMAN (868-1185): 1.34e-115: 392: 29.25
+	Hs
		617157 CTNB1_HUMAN (1-781): 0: 626: 100.00		PTPRZ_HUMAN (333-1185): 1.59e-60: 230: 12.89
+	Hs
		617080 CTNB1_HUMAN (1-781): 0: 626: 100.00		PTPRG_HUMAN (289-1185): 4.53e-60: 228: 12.65
+	Mm
		472764 CTNB1_MOUSE (1-781): 0: 624: 99.87		PTPRQ_MOUSE (912-1183): 1.7e-37: 156: 33.33
+	Hs
		441183 CTNB1_HUMAN (1-781): 0: 626: 100.00		PTPRC_HUMAN (912-1177): 3.42e-24: 112: 26.99