HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: EIF3A (Q14152)
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185)
Gene: EIF3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34316702
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 1382
+	Hs
		717562 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		YLPM1_HUMAN (774-1359): 8.27e-43: 174: 21.91
+	Hs
		718128 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MINT_HUMAN (485-1376): 2.77e-41: 169: 13.43
+	Hs
		1049625 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		EIF3A_HUMAN (1-1382): 3.42e-120: 410: 100.00
+	Hs
		717688 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MAP1A_HUMAN (494-1117): 2.75e-30: 133: 13.68
+	Hs
		717848 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PLEC_HUMAN (497-1343): 1.73e-18: 94.5: 13.97
+	Hs
		718062 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MY18A_HUMAN (532-955): 1.34e-09: 65.3: 16.18
+	Hs
		833030 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		YLPM1_HUMAN (774-1359): 8.27e-43: 174: 21.91
+	Hs
		584903 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		YLPM1_HUMAN (774-1359): 8.27e-43: 174: 21.91
+	Hs
		1078906 TRIM5_HUMAN (9-190): 3.01e-48: 170: 14.89		ITSN1_HUMAN (539-880): 4.76e-22: 106: 18.54
+	Hs
		528393 TRIM6_HUMAN (5-189): 2.83e-49: 173: 16.67		MYH6_HUMAN (366-1087): 4.95e-21: 102: 10.45
+	Hs
		584968 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		PLEC_HUMAN (497-1343): 1.73e-18: 94.5: 13.97
+	Hs
		522639 TRIM6_HUMAN (5-189): 2.83e-49: 173: 16.67		MYH7_HUMAN (83-989): 5.61e-18: 92.8: 10.62
+	Hs
		1078867 DTX3_HUMAN (17-62): 3.98e-10: 62.2: 39.13		ITSN1_HUMAN (539-880): 4.76e-22: 106: 18.54
+	Hs
		282514 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		DESP_HUMAN (478-1060): 3.57e-11: 70.4: 13.18