HitPredict

Interactor 1: 2AAA (P30153)
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2Aa) (Medium tumor antigen-associated 61 kDa protein) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha)
Gene: PPP2R1A

Interactor 2: INT1 (Q8N201)
Integrator complex subunit 1 (Int1)
Gene: INTS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.906

The method score is based on:

Property Details
Experiments 26496610, 28330616, 33961781, 20133760
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HEAT_2~INT1_R3
Common GO terms GO:0005634 - nucleus
GO:0016020 - membrane
GO:0160232 - INTAC complex
GO:0160240 - RNA polymerase II transcription initiation surveillance
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 589
Hs

1 2190
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025