HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: UBP39 (Q53GS9)
Ubiquitin carboxyl-terminal hydrolase 39 (EC 3.4.19.12) (SAD1 homolog) (U4/U6.U5 tri-snRNP-associated 65 kDa protein)
Gene: USP39

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34316702
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 326 Hs			1 565
+	Hs
		718079 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06
+	Hs
		718324 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		UBP22_HUMAN (123-560): 1.99e-114: 351: 17.39
+	Hs
		718415 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06
+	Hs
		1019313 TRI26_HUMAN (5-210): 1e-49: 175: 16.59		UBP39_HUMAN (1-565): 2.92e-163: 478: 100.00
+	Hs
		1108527 PCGF3_HUMAN (4-228): 4.43e-72: 225: 34.03		UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06
+	Hs
		1273848 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06
+	Hs
		1273836 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06
+	Hs
		1223388 TRI22_HUMAN (1-198): 2.92e-50: 175: 14.56		UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06
+	Mm
		1149466 RING2_MOUSE (7-227): 5.77e-50: 171: 16.61		UBP7_MOUSE (10-557): 3.07e-116: 372: 14.24
+	Hs
		271183 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83
+	Hs
		271032 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83
+	Hs
		271189 TRIM5_HUMAN (9-190): 3.01e-48: 170: 14.89		UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83
+	Hs
		1316715 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		UBP21_HUMAN (223-560): 2.89e-97: 308: 18.85
+	Hs
		717585 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		UBP11_HUMAN (439-556): 3.89e-09: 61.6: 31.09
+	Hs
		1311542 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		UBP42_HUMAN (225-557): 2.68e-78: 270: 24.42
+	Hs
		800578 TRI26_HUMAN (5-210): 1e-49: 175: 16.59		UBP5_HUMAN (13-493): 7.35e-87: 288: 15.81
+	Hs
		718382 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		UBP11_HUMAN (439-556): 3.89e-09: 61.6: 31.09
+	Hs
		1019375 TRI26_HUMAN (5-210): 1e-49: 175: 16.59		UBP36_HUMAN (225-564): 4.97e-62: 223: 20.69
+	Hs
		1257026 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		UBP33_HUMAN (411-564): 3.53e-45: 173: 26.54
+	Hs
		584941 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		UBP4_HUMAN (222-340): 1.69e-10: 65.9: 33.33