HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: SYNE1 (Q8NF91)
Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)
Gene: SYNE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	24457600, 34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 8797
+	Hs
		1244129 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		SYNE1_HUMAN (1-8797): 0: 1912: 100.00
+	Hs
		164573 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN2_HUMAN (18-355): 7.94e-49: 197: 39.12
+	Hs
		717728 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		DYST_HUMAN (12-1547): 1.58e-42: 177: 13.83
+	Hs
		718187 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN4_HUMAN (18-354): 7.24e-42: 174: 35.10
+	Hs
		717848 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PLEC_HUMAN (7019-8757): 8.37e-37: 158: 9.89
+	Hs
		718225 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN5_HUMAN (6622-8751): 1.41e-33: 147: 12.27
+	Hs
		717709 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTB2_HUMAN (4116-5904): 9.82e-28: 128: 9.49
+	Hs
		718318 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MACF1_HUMAN (7352-8757): 1.08e-27: 128: 11.64
+	Hs
		513833 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		DMD_HUMAN (7123-8762): 1.08e-26: 124: 10.66
+	Hs
		717799 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN1_HUMAN (7955-8728): 7.08e-25: 118: 13.61
+	Hs
		717542 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		UTRN_HUMAN (7111-8757): 2.11e-24: 117: 11.28
+	Hs
		584968 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		PLEC_HUMAN (7019-8757): 8.37e-37: 158: 9.89
+	Hs
		282627 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		SPTB2_HUMAN (4116-5904): 9.82e-28: 128: 9.49
+	Hs
		282645 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		SPTN1_HUMAN (7955-8728): 7.08e-25: 118: 13.61
+	Hs
		963368 DTX3_HUMAN (17-62): 3.98e-10: 62.2: 39.13		SPTB2_HUMAN (4116-5904): 9.82e-28: 128: 9.49