Protein: IGHA1
Immunoglobulin heavy constant alpha 1 (Ig alpha-1 chain C region) (Ig alpha-1 chain C region BUR) (Ig alpha-1 chain C region TRO)

Gene: IGHA1
Organism: Homo sapiens
Interactions: 149
UniProt ID: P01876

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0003094 - glomerular filtration
GO:0003823 - antigen binding
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

354036

FCAR
Immunoglobulin alpha Fc receptor

1

8

Small-scale

0.647

High

126328

MATN2
Matrilin-2

1

10

High-throughput

0.575

High

198342

KLK10
Kallikrein-10

1

8

High-throughput

0.575

High

341332

PLMN
Plasminogen

1

1

High-throughput

0.575

High

353181

KVD40
Immunoglobulin kappa variable 2D-40

1

14

High-throughput

0.575

High

353189

KV320
Immunoglobulin kappa variable 3-20

1

11

High-throughput

0.575

High

353205

LV147
Immunoglobulin lambda variable 1-47

1

17

High-throughput

0.575

High

354020

FINC
Fibronectin

1

7

High-throughput

0.575

High

354022

ALBU
Albumin

1

5

High-throughput

0.575

High

354028

HEP2
Heparin cofactor 2

1

1

High-throughput

0.575

High

354030

IGLC1
Immunoglobulin lambda constant 1

1

16

High-throughput

0.575

High

354035

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

4

High-throughput

0.575

High

354040

TRY3
Trypsin-3

1

9

High-throughput

0.575

High

354044

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

1

5

High-throughput

0.575

High

354074

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

9

High-throughput

0.575

High

354078

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

1

High-throughput

0.575

High

354096

FNDC5
Fibronectin type III domain-containing protein 5

1

5

High-throughput

0.575

High

354141

Q9UL92
Myosin-reactive immunoglobulin heavy chain variable region

1

18

High-throughput

0.575

High

354038

ITPI2
Protein ITPRID2

2

1

High-throughput

0.552

High

354077

HBM
Hemoglobin subunit mu

2

4

High-throughput

0.552

High

354050

GDF10
Growth/differentiation factor 10

1

0

High-throughput

0.546

High

354114

HAVR1
Hepatitis A virus cellular receptor 1

1

0

Small-scale

0.546

High

354134

CA2D2
Voltage-dependent calcium channel subunit alpha-2/delta-2

1

0

High-throughput

0.546

High

354054

TF2B
Transcription initiation factor IIB

2

3

High-throughput

0.504

High

354066

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

2

1

High-throughput

0.504

High

354076

ICE2
Little elongation complex subunit 2

2

2

High-throughput

0.504

High

354093

FRMD1
FERM domain-containing protein 1

2

5

High-throughput

0.504

High

354094

ZN491
Zinc finger protein 491

2

1

High-throughput

0.504

High

354118

SNX27
Sorting nexin-27

2

10

High-throughput

0.504

High

354120

TM237
Transmembrane protein 237

2

1

High-throughput

0.504

High

354127

DDX31
ATP-dependent DNA helicase DDX31

2

8

High-throughput

0.504

High

354032

CADH1
Cadherin-1

1

2

Small-scale

0.479

High

354034

NCK1
SH2/SH3 adapter protein NCK1

1

15

Small-scale

0.479

High

354037

APC
Adenomatous polyposis coli protein

1

1

Small-scale

0.479

High

354055

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

134508

FCN1
Ficolin-1

1

5

Small-scale

0.457

High

127657

CCRL2
C-C chemokine receptor-like 2

1

11

High-throughput

0.445

High

168487

SCAM2
Secretory carrier-associated membrane protein 2

1

1

High-throughput

0.445

High

328084

SG1D1
Secretoglobin family 1D member 1

1

5

High-throughput

0.445

High

354016

K1C14
Keratin, type I cytoskeletal 14

1

10

High-throughput

0.445

High

354017

APOA1
Apolipoprotein A-I

1

3

High-throughput

0.445

High

354018

APOC1
Apolipoprotein C-I

1

2

High-throughput

0.445

High

354019

FIBA
Fibrinogen alpha chain [Cleaved into: Fibrinopeptide A; Fibrinogen alpha chain]

1

5

High-throughput

0.445

High

354021

TTHY
Transthyretin

1

1

High-throughput

0.445

High

354023

TRFE
Serotransferrin

1

3

High-throughput

0.445

High

354024

K2C1
Keratin, type II cytoskeletal 1

1

5

High-throughput

0.445

High

354025

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

6

High-throughput

0.445

High

354026

F13B
Coagulation factor XIII B chain

1

5

Small-scale

0.445

High

354031

CLUS
Clusterin

1

1

High-throughput

0.445

High

354033

K1C10
Keratin, type I cytoskeletal 10

1

12

High-throughput

0.445

High

354039

CCR1
C-C chemokine receptor type 1

1

10

High-throughput

0.445

High

354041

K1C9
Keratin, type I cytoskeletal 9

1

11

High-throughput

0.445

High

354043

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

4

High-throughput

0.445

High

354046

TGM4
Protein-glutamine gamma-glutamyltransferase 4

1

1

High-throughput

0.445

High

354057

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

3

High-throughput

0.445

High

354059

FADD
FAS-associated death domain protein

1

2

High-throughput

0.445

High

354063

I5P1
Inositol polyphosphate-5-phosphatase A

1

1

High-throughput

0.445

High

354065

STK11
Serine/threonine-protein kinase STK11

1

1

High-throughput

0.445

High

354071

FBLN7
Fibulin-7

1

5

High-throughput

0.445

High

354097

AT11C
Phospholipid-transporting ATPase IG

1

2

High-throughput

0.445

High

354101

NPB
Neuropeptide B

1

2

High-throughput

0.445

High

354102

PARD3
Partitioning defective 3 homolog

1

3

High-throughput

0.445

High

354106

ITLN2
Intelectin-2

1

5

High-throughput

0.445

High

354111

PMEPA
Protein TMEPAI

1

2

High-throughput

0.445

High

354122

EGFL8
Epidermal growth factor-like protein 8

1

14

High-throughput

0.445

High

354139

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

7

High-throughput

0.445

High

354142

HYOU1
Hypoxia up-regulated protein 1

1

2

High-throughput

0.445

High

146787

CDKA1
Cyclin-dependent kinase 2-associated protein 1

1

1

High-throughput

0.437

High

208971

NCK2
Cytoplasmic protein NCK2

1

14

Small-scale

0.437

High

260434

PITX3
Pituitary homeobox 3

1

3

Small-scale

0.437

High

354115

CK5P3
CDK5 regulatory subunit-associated protein 3

1

1

High-throughput

0.437

High

354029

CATL1
Procathepsin L

1

0

High-throughput

0.426

High

354047

CLCN2
Chloride channel protein 2

1

0

High-throughput

0.426

High

354098

TM116
Transmembrane protein 116

1

0

High-throughput

0.426

High

354113

CHM4C
Charged multivesicular body protein 4c

1

0

High-throughput

0.426

High

354116

LOXL4
Lysyl oxidase homolog 4

1

0

High-throughput

0.426

High

354119

PRAP1
Proline-rich acidic protein 1

1

0

High-throughput

0.426

High

354125

SPEF2
Sperm flagellar protein 2

1

0

High-throughput

0.426

High

354132

GKN1
Gastrokine-1

1

0

High-throughput

0.426

High

354135

UNC79
Protein unc-79 homolog

1

0

High-throughput

0.426

High

64478

GOG8A
Golgin subfamily A member 8A

1

4

High-throughput

0.407

High

127087

FOXN3
Forkhead box protein N3

1

3

High-throughput

0.407

High

159451

QCR8
Cytochrome b-c1 complex subunit 8

1

1

High-throughput

0.407

High

180530

MAGB4
Melanoma-associated antigen B4

1

4

High-throughput

0.407

High

312694

CXB5
Gap junction beta-5 protein

1

7

High-throughput

0.407

High

330378

CX001
Putative transmembrane protein CXorf1

1

1

High-throughput

0.407

High

354027

JUN
Transcription factor Jun

1

1

High-throughput

0.407

High

354042

MTREX
Exosome RNA helicase MTR4

1

2

High-throughput

0.407

High

354048

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

5

High-throughput

0.407

High

354049

RCAN1
Calcipressin-1

1

1

High-throughput

0.407

High

354051

TIM10
Mitochondrial import inner membrane translocase subunit Tim10

1

3

High-throughput

0.407

High

354053

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

7

High-throughput

0.407

High

354056

TWF1
Twinfilin-1

1

2

High-throughput

0.407

High

354058

STK4
Serine/threonine-protein kinase 4

1

8

High-throughput

0.407

High

354060

SNW1
SNW domain-containing protein 1

1

1

High-throughput

0.407

High

354061

RUNX2
Runt-related transcription factor 2

1

2

High-throughput

0.407

High

354062

RCAN2
Calcipressin-2

1

1

High-throughput

0.407

High

354064

COG2
Conserved oligomeric Golgi complex subunit 2

1

1

High-throughput

0.407

High

354067

CR021
UPF0711 protein C18orf21

1

6

High-throughput

0.407

High

354068

PKHG6
Pleckstrin homology domain-containing family G member 6

1

1

High-throughput

0.407

High

354069

T176B
Transmembrane protein 176B

1

2

High-throughput

0.407

High

354070

KLH22
Kelch-like protein 22

1

3

High-throughput

0.407

High

354075

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

7

High-throughput

0.407

High

354080

SFXN4
Sideroflexin-4

1

5

High-throughput

0.407

High

354082

CTR9
RNA polymerase-associated protein CTR9 homolog

1

3

High-throughput

0.407

High

354083

SPNS3
Protein spinster homolog 3

1

1

High-throughput

0.407

High

354084

CIR1
Corepressor interacting with RBPJ 1

1

6

High-throughput

0.407

High

354085

ZN695
Zinc finger protein 695

1

1

High-throughput

0.407

High

354086

RHG12
Rho GTPase-activating protein 12

1

5

High-throughput

0.407

High

354087

SLX4
Structure-specific endonuclease subunit SLX4

1

3

High-throughput

0.407

High

354088

ELOA2
Elongin-A2

1

4

High-throughput

0.407

High

354089

RIBC1
RIB43A-like with coiled-coils protein 1

1

2

High-throughput

0.407

High

354091

COMD1
COMM domain-containing protein 1

1

1

High-throughput

0.407

High

354095

GDPD1
Lysophospholipase D GDPD1

1

3

High-throughput

0.407

High

354099

PNMA1
Paraneoplastic antigen Ma1

1

1

High-throughput

0.407

High

354103

CHAC2
Glutathione-specific gamma-glutamylcyclotransferase 2

1

1

High-throughput

0.407

High

354107

CRGN
Gamma-crystallin N

1

1

High-throughput

0.407

High

354108

DDX17
Probable ATP-dependent RNA helicase DDX17

1

1

High-throughput

0.407

High

354109

TANK
TRAF family member-associated NF-kappa-B activator

1

2

High-throughput

0.407

High

354110

PIGT
GPI transamidase component PIG-T

1

6

High-throughput

0.407

High

354112

GTPB3
tRNA modification GTPase GTPBP3, mitochondrial

1

2

High-throughput

0.407

High

354121

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

10

High-throughput

0.407

High

354123

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.407

High

354124

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

9

High-throughput

0.407

High

354128

QTRT2
Queuine tRNA-ribosyltransferase accessory subunit 2

1

1

High-throughput

0.407

High

354130

COE2
Transcription factor COE2

1

5

High-throughput

0.407

High

354133

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

4

High-throughput

0.407

High

354136

KLF15
Krueppel-like factor 15

1

6

High-throughput

0.407

High

354137

PHF11
PHD finger protein 11

1

9

High-throughput

0.407

High

354140

NXT1
NTF2-related export protein 1

1

1

High-throughput

0.407

High

67751

ZBBX
Zinc finger B-box domain-containing protein 1

1

0

High-throughput

0.232

Low

153205

ACOT8
Acyl-coenzyme A thioesterase 8

1

0

High-throughput

0.232

Low

256869

NPHP4
Nephrocystin-4

1

0

High-throughput

0.232

Low

354045

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.232

Low

354052

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.232

Low

354072

EAPP
E2F-associated phosphoprotein

1

0

High-throughput

0.232

Low

354073

Q5JQP4
DNA polymerase

1

0

High-throughput

0.232

Low

354079

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.232

Low

354081

PBIR3
PABIR family member 1

1

0

High-throughput

0.232

Low

354090

TBC19
TBC1 domain family member 19

1

0

High-throughput

0.232

Low

354092

CJ053
UPF0728 protein C10orf53

1

0

High-throughput

0.232

Low

354100

CC148
Coiled-coil domain-containing protein 148

1

0

High-throughput

0.232

Low

354104

RN141
RING finger protein 141

1

0

High-throughput

0.232

Low

354105

CKAP2
Cytoskeleton-associated protein 2

1

0

High-throughput

0.232

Low

354117

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

0

High-throughput

0.232

Low

354126

ATG5
Autophagy protein 5

1

0

High-throughput

0.232

Low

354129

KT3K
Ketosamine-3-kinase

1

0

High-throughput

0.232

Low

354131

ZCC17
Zinc finger CCHC domain-containing protein 17

1

0

High-throughput

0.232

Low

354138

SRTD3
SERTA domain-containing protein 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024