HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.681

Property	Details
Experiments	25605328, 20601937, 20800574
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, molecular sieving
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016604 - nuclear body
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 1102
+	Hs
		718415 PCGF2_HUMAN (1-320): 1.04e-117: 344: 61.36		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1108527 PCGF3_HUMAN (4-228): 4.43e-72: 225: 34.03		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273848 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273836 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1223388 TRI22_HUMAN (1-198): 2.92e-50: 175: 14.56		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		1273821 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Mm
		1149466 RING2_MOUSE (7-227): 5.77e-50: 171: 16.61		UBP7_MOUSE (1-1102): 0: 1159: 99.00
+	Hs
		1273786 CHFR_HUMAN (8-168): 2.7e-31: 125: 19.14		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		988002 RING1_HUMAN (7-115): 2.38e-30: 120: 25.46		UBP7_HUMAN (1-1102): 0: 1165: 100.00
+	Hs
		718324 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		UBP22_HUMAN (45-521): 2.51e-107: 347: 16.43
+	Hs
		1173873 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		UBP34_HUMAN (125-644): 3.97e-99: 348: 18.81
+	Hs
		1273718 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		USP9X_HUMAN (173-554): 7.42e-97: 341: 23.08
+	Hs
		1311542 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		UBP42_HUMAN (162-683): 1.67e-95: 334: 18.44
+	Hs
		1019375 TRI26_HUMAN (5-210): 1e-49: 175: 16.59		UBP36_HUMAN (165-651): 1.45e-94: 328: 18.13