HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: DIDO1 (Q9BTC0)
Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1)
Gene: DIDO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24457600, 34316702
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0097190 - apoptotic signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 326 Hs			1 2240
+	Hs
		1311529 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		DIDO1_HUMAN (1-2240): 0: 732: 100.00
+	Hs
		718364 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PRC2C_HUMAN (27-1904): 3.9e-50: 199: 9.83
+	Hs
		718128 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MINT_HUMAN (10-2011): 1.36e-47: 191: 9.73
+	Hs
		717562 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		YLPM1_HUMAN (1365-2223): 2.36e-41: 170: 13.66
+	Hs
		718320 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PHF8_HUMAN (236-386): 7.12e-24: 112: 23.31
+	Hs
		409729 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		CO5A2_HUMAN (839-1926): 3.47e-23: 110: 9.32
+	Hs
		718055 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		TITIN_HUMAN (19-1290): 3.32e-21: 104: 10.49
+	Hs
		718326 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		718061 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PHF3_HUMAN (1921-2190): 3.11e-09: 64.7: 14.29
+	Hs
		833030 PCGF1_HUMAN (2-229): 5.96e-62: 199: 36.33		YLPM1_HUMAN (1365-2223): 2.36e-41: 170: 13.66
+	Hs
		584903 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		YLPM1_HUMAN (1365-2223): 2.36e-41: 170: 13.66
+	Hs
		1304155 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		CXXC1_HUMAN (245-393): 2.59e-34: 144: 26.75
+	Hs
		135026 TRI38_HUMAN (1-203): 9.11e-44: 158: 16.51		TCEA2_HUMAN (577-816): 6.11e-40: 153: 19.20
+	Hs
		1019385 TRI26_HUMAN (5-210): 1e-49: 175: 16.59		PHF8_HUMAN (236-386): 7.12e-24: 112: 23.31
+	Hs
		1300927 PCGF6_HUMAN (2-235): 2.13e-61: 201: 35.12		CIC_HUMAN (2-1657): 2.53e-13: 78.4: 7.87
+	Hs
		1264788 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		TITIN_HUMAN (19-1290): 3.32e-21: 104: 10.49
+	Hs
		585039 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		CIC_HUMAN (2-1657): 2.53e-13: 78.4: 7.87
+	Hs
		1019387 TRI26_HUMAN (5-210): 1e-49: 175: 16.59		SRRM2_HUMAN (6-1279): 6.35e-14: 80.3: 8.36
+	Hs
		1223389 TRI22_HUMAN (1-198): 2.92e-50: 175: 14.56		CIC_HUMAN (2-1657): 2.53e-13: 78.4: 7.87
+	Hs
		1300908 RING2_HUMAN (7-227): 8.37e-50: 170: 16.61		CIC_HUMAN (2-1657): 2.53e-13: 78.4: 7.87