Protein: PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

Gene: PP4R1, PPP4R1
Organism: Homo sapiens
Interactions: 61
UniProt ID: Q8TF05

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0006468 - protein phosphorylation
GO:0007165 - signal transduction
GO:0019888 - protein phosphatase regulator activity
GO:0030289 - protein phosphatase 4 complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

952005

PP4C
Serine/threonine-protein phosphatase 4 catalytic subunit

9

19

Small-scale

0.975

High

977548

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

5

20

High-throughput

0.833

High

717915

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

6

High-throughput

0.811

High

994309

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

3

20

High-throughput

0.779

High

718153

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

6

High-throughput

0.691

High

1156558

CCDC6
Coiled-coil domain-containing protein 6

4

5

High-throughput

0.638

High

1145901

RBP1
RalA-binding protein 1

4

4

High-throughput

0.630

High

246069

KIF1B
Kinesin-like protein KIF1B

2

1

High-throughput

0.628

High

173127

XPO1
Exportin-1

1

5

High-throughput

0.618

High

282018

MPPB
Mitochondrial-processing peptidase subunit beta

3

2

High-throughput

0.609

High

1124506

MAP7
Ensconsin

2

4

High-throughput

0.574

High

1241915

FBX42
F-box only protein 42

2

2

High-throughput

0.558

High

1090815

TRAF2
TNF receptor-associated factor 2

1

3

Small-scale

0.552

High

254195

CTND1
Catenin delta-1

1

1

High-throughput

0.536

High

451037

LDHB
L-lactate dehydrogenase B chain

1

1

High-throughput

0.536

High

733400

CCR1
C-C chemokine receptor type 1

1

1

High-throughput

0.536

High

1353463

GDF3
Growth/differentiation factor 3

1

1

High-throughput

0.536

High

1353466

KLH11
Kelch-like protein 11

1

2

High-throughput

0.536

High

1353458

CEP63
Centrosomal protein of 63 kDa

2

2

High-throughput

0.526

High

1353464

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.513

High

1353469

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.513

High

963109

S61A1
Protein transport protein Sec61 subunit alpha isoform 1

1

1

High-throughput

0.489

High

1353468

NTNG1
Netrin-G1

1

1

High-throughput

0.489

High

167936

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

10

Small-scale

0.479

High

177913

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

14

Small-scale

0.479

High

188323

HDAC3
Histone deacetylase 3

1

3

Small-scale

0.479

High

412312

NTRK1
High affinity nerve growth factor receptor

1

4

High-throughput

0.479

High

831117

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

958477

ACTZ
Alpha-centractin

1

3

High-throughput

0.479

High

964687

DCAF7
DDB1- and CUL4-associated factor 7

1

2

High-throughput

0.479

High

997051

TBA4A
Tubulin alpha-4A chain

1

3

High-throughput

0.479

High

1047924

TLE2
Transducin-like enhancer protein 2

1

5

High-throughput

0.479

High

1048044

TLE3
Transducin-like enhancer protein 3

1

7

High-throughput

0.479

High

1113813

CUL3
Cullin-3

1

3

High-throughput

0.479

High

1254789

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

1259372

TBA1A
Tubulin alpha-1A chain

1

3

High-throughput

0.479

High

1325498

FBXW8
F-box/WD repeat-containing protein 8

1

5

High-throughput

0.479

High

1327570

WDTC1
WD and tetratricopeptide repeats protein 1

1

7

High-throughput

0.479

High

1353460

SKI8
Superkiller complex protein 8

1

1

High-throughput

0.479

High

1353461

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.479

High

1353462

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1353467

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1353470

TRAF6
TNF receptor-associated factor 6

1

4

Small-scale

0.479

High

320401

SASH1
SAM and SH3 domain-containing protein 1

1

0

Small-scale

0.460

High

984213

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.458

High

638480

FPR1
fMet-Leu-Phe receptor

1

1

High-throughput

0.445

High

1208937

DCA10
DDB1- and CUL4-associated factor 10

1

3

High-throughput

0.437

High

1227137

A16L1
Autophagy-related protein 16-1

1

8

High-throughput

0.437

High

1340760

COP1
E3 ubiquitin-protein ligase COP1

1

2

High-throughput

0.437

High

1352244

DCA11
DDB1- and CUL4-associated factor 11

1

4

High-throughput

0.437

High

1353459

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

2

High-throughput

0.437

High

1119218

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

1219523

ANR22
Ankyrin repeat domain-containing protein 22

1

3

High-throughput

0.407

High

486872

C1S
Complement C1s subcomponent

2

0

High-throughput

0.328

High

1353465

DISC1
Disrupted in schizophrenia 1 protein

2

0

High-throughput

0.307

High

282401

MED24
Mediator of RNA polymerase II transcription subunit 24

1

0

High-throughput

0.279

Low

328319

NDUB4
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4

1

0

High-throughput

0.279

Low

1272944

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

0

High-throughput

0.279

Low

1353457

DCAF4
DDB1- and CUL4-associated factor 4

1

0

High-throughput

0.249

Low

947027

DSCR9
Down syndrome critical region protein 9

1

0

High-throughput

0.238

Low

262274

SCN2B
Sodium channel regulatory subunit beta-2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025