HitPredict

Interactor 1: BMI1 (P35226)
Polycomb complex protein BMI-1 (Polycomb group RING finger protein 4) (RING finger protein 51)
Gene: BMI1

Interactor 2: SPTN4 (Q9H254)
Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)
Gene: SPTBN4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	34316702
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 326 Hs			1 2564
+	Hs
		717709 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTB2_HUMAN (624-2551): 4.56e-61: 235: 17.42
+	Hs
		164573 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN2_HUMAN (507-2546): 2.8e-51: 203: 18.94
+	Hs
		717799 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN1_HUMAN (259-1728): 1.07e-47: 191: 15.07
+	Hs
		718225 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		SPTN5_HUMAN (879-2480): 1.68e-34: 148: 15.92
+	Hs
		211495 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		ACTN4_HUMAN (60-639): 2.57e-113: 386: 39.93
+	Hs
		717848 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		PLEC_HUMAN (233-1186): 4.07e-17: 91.3: 11.29
+	Hs
		717542 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		UTRN_HUMAN (212-2049): 2.24e-15: 85.6: 10.34
+	Hs
		521481 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		ACTN1_HUMAN (1813-2273): 3.24e-14: 80.9: 10.24
+	Hs
		717728 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		DYST_HUMAN (971-1734): 2.66e-10: 68.7: 12.78
+	Hs
		718318 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		MACF1_HUMAN (887-1821): 3.14e-10: 68.7: 13.90
+	Hs
		513833 BMI1_HUMAN (1-326): 1.43e-153: 435: 100.00		DMD_HUMAN (254-1241): 2.74e-09: 65.5: 9.46
+	Hs
		282627 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		SPTB2_HUMAN (624-2551): 4.56e-61: 235: 17.42
+	Hs
		963368 DTX3_HUMAN (17-62): 3.98e-10: 62.2: 39.13		SPTB2_HUMAN (624-2551): 4.56e-61: 235: 17.42
+	Hs
		282645 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		SPTN1_HUMAN (259-1728): 1.07e-47: 191: 15.07
+	Hs
		584968 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		PLEC_HUMAN (233-1186): 4.07e-17: 91.3: 11.29
+	Hs
		521464 RO52_HUMAN (5-198): 5.75e-52: 180: 18.78		ACTN1_HUMAN (1813-2273): 3.24e-14: 80.9: 10.24
+	Hs
		282506 RNF8_HUMAN (2-101): 3.38e-21: 95.7: 25.00		ACTN1_HUMAN (1813-2273): 3.24e-14: 80.9: 10.24