HitPredict

Interactor 1: PCGF2 (P35227)
Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144)
Gene: PCGF2

Interactor 2: UBP11 (P51784)
Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11)
Gene: USP11

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.60	0.597

Property	Details
Experiments	20601937
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 344 Hs			1 963
+	Hs
		717585 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		UBP11_HUMAN (1-963): 0: 849: 100.00
+	Hs
		850161 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		UBP11_HUMAN (1-963): 0: 849: 100.00
+	Hs
		584941 RO52_HUMAN (8-210): 4.32e-32: 127: 15.02		UBP4_HUMAN (73-933): 0: 656: 44.79
+	Hs
		1257026 PCGF6_HUMAN (2-227): 3.54e-58: 193: 35.47		UBP33_HUMAN (223-945): 9.3e-109: 360: 18.55
+	Hs
		718415 PCGF2_HUMAN (1-344): 8.96e-118: 345: 100.00		UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17
+	Hs
		718324 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		UBP22_HUMAN (597-930): 2.39e-62: 222: 17.88
+	Hs
		718079 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17
+	Hs
		1108527 PCGF3_HUMAN (4-230): 3.51e-66: 210: 33.48		UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17
+	Hs
		271183 PCGF6_HUMAN (2-227): 3.54e-58: 193: 35.47		UBP2_HUMAN (609-936): 9.85e-61: 220: 23.37
+	Hs
		1273836 PCGF1_HUMAN (2-232): 1.01e-61: 199: 35.42		UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17
+	Hs
		1273848 PCGF6_HUMAN (2-227): 3.54e-58: 193: 35.47		UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17
+	Hs
		718357 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		UBP15_HUMAN (485-644): 1.32e-17: 90.4: 10.18
+	Hs
		1316715 PCGF6_HUMAN (2-227): 3.54e-58: 193: 35.47		UBP21_HUMAN (778-935): 1.96e-48: 183: 38.61
+	Hs
		1273821 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17
+	Hs
		271032 RO52_HUMAN (8-210): 4.32e-32: 127: 15.02		UBP2_HUMAN (609-936): 9.85e-61: 220: 23.37
+	Hs
		1223388 TRI22_HUMAN (1-271): 1.46e-33: 131: 15.12		UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17
+	Hs
		1273786 CHFR_HUMAN (8-150): 4.68e-28: 116: 17.93		UBP7_HUMAN (607-959): 9.02e-54: 205: 15.17
+	Hs
		301435 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		UBP19_HUMAN (496-656): 3.05e-21: 102: 7.96
+	Hs
		301359 RO52_HUMAN (8-210): 4.32e-32: 127: 15.02		UBP19_HUMAN (496-656): 3.05e-21: 102: 7.96
+	Hs
		585101 RO52_HUMAN (8-210): 4.32e-32: 127: 15.02		UBP15_HUMAN (485-644): 1.32e-17: 90.4: 10.18