HitPredict

Interactor 1: PCGF2 (P35227)
Polycomb group RING finger protein 2 (DNA-binding protein Mel-18) (RING finger protein 110) (Zinc finger protein 144)
Gene: PCGF2

Interactor 2: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016604 - nuclear body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 344 Hs			1 342
+	Hs
		718223 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		SC31B_HUMAN (23-336): 4.36e-52: 187: 17.38
+	Hs
		902923 PCGF3_HUMAN (4-230): 3.51e-66: 210: 33.48		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		903014 PCGF1_HUMAN (2-232): 1.01e-61: 199: 35.42		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		903017 PCGF6_HUMAN (2-227): 3.54e-58: 193: 35.47		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		902951 PCGF5_HUMAN (1-221): 5.43e-53: 177: 31.88		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		903005 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Mm
		903076 RING2_MOUSE (4-234): 2.19e-45: 159: 17.49		DCAF7_MOUSE (1-342): 5.45e-87: 267: 100.00
+	Mm
		1194979 RING2_MOUSE (4-234): 2.19e-45: 159: 17.49		Q80ZU1_MOUSE (1-342): 2.67e-85: 262: 99.71
+	Hs
		717626 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Mm
		1141971 RING2_MOUSE (4-234): 2.19e-45: 159: 17.49		RBBP7_MOUSE (10-342): 1.03e-68: 222: 14.51
+	Hs
		902886 RING1_HUMAN (3-127): 4.75e-28: 114: 23.26		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Mm
		1141950 RING2_MOUSE (4-234): 2.19e-45: 159: 17.49		RBBP4_MOUSE (10-342): 2.39e-68: 221: 13.98
+	Hs
		997870 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98
+	Hs
		718175 BMI1_HUMAN (1-341): 3.88e-98: 295: 61.40		WDR33_HUMAN (221-341): 6.91e-16: 81: 14.05
+	Dm
		1279331 Q9VV77_DROME (4-230): 3.72e-58: 189: 34.19		EBI_DROME (104-342): 5.77e-41: 153: 15.98
+	Hs
		903492 PCGF6_HUMAN (2-227): 3.54e-58: 193: 35.47		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		903455 RING2_HUMAN (4-234): 2.68e-45: 159: 17.49		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Mm
		903677 RING2_MOUSE (4-234): 2.19e-45: 159: 17.49		WDR5_MOUSE (208-342): 8.98e-29: 115: 11.85
+	Hs
		903159 RING1_HUMAN (3-127): 4.75e-28: 114: 23.26		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		282600 RNF8_HUMAN (2-101): 6.37e-23: 101: 25.00		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85