Protein: SMU1
WD40 repeat-containing protein SMU1 (Smu-1 suppressor of mec-8 and unc-52 protein homolog) [Cleaved into: WD40 repeat-containing protein SMU1, N-terminally processed]

Gene: SMU1
Organism: Homo sapiens
Interactions: 187
UniProt ID: Q2TAY7

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1024902

RED
Protein Red

9

5

Small-scale

0.975

High

1103035

CERT
Ceramide transfer protein

2

2

High-throughput

0.783

High

1064361

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

2

5

High-throughput

0.754

High

1102992

PRP8
Pre-mRNA-processing-splicing factor 8

2

3

High-throughput

0.754

High

300167

PRP6
Pre-mRNA-processing factor 6

1

11

High-throughput

0.691

High

1103010

MR1L1
MORF4 family-associated protein 1-like 1

5

2

High-throughput

0.661

High

313293

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

3

2

High-throughput

0.650

High

1102987

SMU1
WD40 repeat-containing protein SMU1

1

17

Small-scale

0.647

High

159066

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

12

High-throughput

0.618

High

631175

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.618

High

895800

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

8

High-throughput

0.618

High

908636

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

15

High-throughput

0.618

High

929487

RACK1
Small ribosomal subunit protein RACK1

1

19

High-throughput

0.618

High

932189

ACTC
Actin, alpha cardiac muscle 1

1

8

High-throughput

0.618

High

943844

RAE1L
mRNA export factor RAE1

1

18

High-throughput

0.618

High

1058218

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

15

Small-scale

0.618

High

1082206

DDB1
DNA damage-binding protein 1

1

13

Small-scale

0.618

High

1102995

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.618

High

1103007

FBXW7
F-box/WD repeat-containing protein 7

1

17

Small-scale

0.618

High

1103025

ANLN
Anillin

1

8

High-throughput

0.618

High

1103033

FZR1
Fizzy-related protein homolog

1

16

High-throughput

0.618

High

1054356

RBM39
RNA-binding protein 39

2

10

High-throughput

0.611

High

211866

TLX3
T-cell leukemia homeobox protein 3

2

11

High-throughput

0.606

High

1103036

MOFA1
MORF4 family-associated protein 1

2

2

High-throughput

0.606

High

875639

MFAP1
Microfibrillar-associated protein 1

2

2

Small-scale

0.600

High

227617

PRKN
E3 ubiquitin-protein ligase parkin

2

19

High-throughput

0.584

High

255833

OBSL1
Obscurin-like protein 1

2

9

Small-scale

0.584

High

346933

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.584

High

1061445

CUL7
Cullin-7

2

4

Small-scale

0.584

High

1085747

IF16
Gamma-interferon-inducible protein 16

2

7

High-throughput

0.584

High

369721

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1087152

H2B2E
Histone H2B type 2-E

1

7

Small-scale

0.561

High

148887

CTRO
Citron Rho-interacting kinase

1

7

High-throughput

0.553

High

268743

SF3B1
Splicing factor 3B subunit 1

1

5

High-throughput

0.536

High

446660

SNRPA
U1 small nuclear ribonucleoprotein A

1

8

High-throughput

0.536

High

448676

RU1C
U1 small nuclear ribonucleoprotein C

1

2

High-throughput

0.536

High

497124

TAU
Microtubule-associated protein tau

1

14

High-throughput

0.536

High

538983

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

3

High-throughput

0.536

High

620506

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

11

High-throughput

0.536

High

742330

SYUA
Alpha-synuclein

1

4

High-throughput

0.536

High

911856

RUXF
Small nuclear ribonucleoprotein F

1

10

High-throughput

0.536

High

924609

GRB2
Growth factor receptor-bound protein 2

1

8

High-throughput

0.536

High

1041692

CUL3
Cullin-3

1

20

High-throughput

0.536

High

1043385

CUL4B
Cullin-4B

1

20

Small-scale

0.536

High

1074128

SF3A1
Splicing factor 3A subunit 1

1

6

High-throughput

0.536

High

1103003

ARRD2
Arrestin domain-containing protein 2

1

6

High-throughput

0.536

High

1103009

ARRD3
Arrestin domain-containing protein 3

1

6

High-throughput

0.536

High

1048331

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

1103015

TSNAX
Translin-associated protein X

1

0

High-throughput

0.513

High

321405

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

6

High-throughput

0.508

High

931192

YBOX1
Y-box-binding protein 1

1

2

High-throughput

0.508

High

1103034

LSM4
U6 snRNA-associated Sm-like protein LSm4

1

12

High-throughput

0.508

High

475845

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

10

High-throughput

0.501

High

117715

MYO1C
Unconventional myosin-Ic

1

5

High-throughput

0.479

High

122800

MEN1
Menin

1

5

High-throughput

0.479

High

136021

ACACB
Acetyl-CoA carboxylase 2

1

12

High-throughput

0.479

High

162805

XPO1
Exportin-1

1

11

High-throughput

0.479

High

210038

PRC1
Protein regulator of cytokinesis 1

1

9

High-throughput

0.479

High

213898

DYRK3
Dual specificity tyrosine-phosphorylation-regulated kinase 3

1

13

Small-scale

0.479

High

214286

SPOP
Speckle-type POZ protein

1

8

High-throughput

0.479

High

233484

NUPR1
Nuclear protein 1

1

5

High-throughput

0.479

High

244523

BRD4
Bromodomain-containing protein 4

1

17

High-throughput

0.479

High

256273

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

15

Small-scale

0.479

High

272161

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

15

High-throughput

0.479

High

294893

RECQ4
ATP-dependent DNA helicase Q4

1

20

High-throughput

0.479

High

298558

UFL1
E3 UFM1-protein ligase 1

1

2

High-throughput

0.479

High

299771

PLPHP
Pyridoxal phosphate homeostasis protein

1

1

High-throughput

0.479

High

304188

UBR5
E3 ubiquitin-protein ligase UBR5

1

10

Small-scale

0.479

High

308761

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

351392

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

4

High-throughput

0.479

High

374315

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

12

High-throughput

0.479

High

378538

OAT
Ornithine aminotransferase, mitochondrial

1

2

High-throughput

0.479

High

379460

MYCN
N-myc proto-oncogene protein

1

18

High-throughput

0.479

High

442202

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

9

High-throughput

0.479

High

449278

LEG1
Galectin-1

1

6

High-throughput

0.479

High

452797

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

487489

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

495537

THIO
Thioredoxin

1

8

High-throughput

0.479

High

499787

CH60
60 kDa heat shock protein, mitochondrial

1

12

High-throughput

0.479

High

517281

PCNA
Proliferating cell nuclear antigen

1

1

High-throughput

0.479

High

518374

ADT3
ADP/ATP translocase 3

1

6

High-throughput

0.479

High

551723

DESP
Desmoplakin

1

16

High-throughput

0.479

High

552860

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

598147

FLNA
Filamin-A

1

14

High-throughput

0.479

High

610864

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

4

High-throughput

0.479

High

622476

CCND1
G1/S-specific cyclin-D1

1

5

Small-scale

0.479

High

622591

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

1

High-throughput

0.479

High

626150

APC
Adenomatous polyposis coli protein

1

20

Small-scale

0.479

High

651350

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

653278

PYR1
Multifunctional protein CAD

1

4

High-throughput

0.479

High

670961

PRDX3
Thioredoxin-dependent peroxide reductase, mitochondrial

1

6

High-throughput

0.479

High

676679

AL1B1
Aldehyde dehydrogenase X, mitochondrial

1

3

High-throughput

0.479

High

682832

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

16

High-throughput

0.479

High

684773

STIP1
Stress-induced-phosphoprotein 1

1

13

High-throughput

0.479

High

685699

PRDX2
Peroxiredoxin-2

1

6

High-throughput

0.479

High

702068

RL9
Large ribosomal subunit protein uL6

1

6

High-throughput

0.479

High

708934

MCM7
DNA replication licensing factor MCM7

1

6

High-throughput

0.479

High

717884

BMI1
Polycomb complex protein BMI-1

1

16

High-throughput

0.479

High

718899

PHB1
Prohibitin 1

1

7

High-throughput

0.479

High

720603

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

726858

FUS
RNA-binding protein FUS

1

15

High-throughput

0.479

High

760094

RL3
Large ribosomal subunit protein uL3

1

7

High-throughput

0.479

High

805687

RL27A
Large ribosomal subunit protein uL15

1

6

High-throughput

0.479

High

808664

YAP1
Transcriptional coactivator YAP1

1

10

High-throughput

0.479

High

843219

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.479

High

877750

FOXA1
Hepatocyte nuclear factor 3-alpha

1

11

High-throughput

0.479

High

894666

DEST
Destrin

1

3

High-throughput

0.479

High

910447

RS14
Small ribosomal subunit protein uS11

1

5

High-throughput

0.479

High

911401

RS11
Small ribosomal subunit protein uS17

1

5

High-throughput

0.479

High

914987

RS4X
Small ribosomal subunit protein eS4, X isoform

1

4

High-throughput

0.479

High

917361

H4
Histone H4

1

8

High-throughput

0.479

High

923039

RL11
Large ribosomal subunit protein uL5

1

4

High-throughput

0.479

High

927819

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

1

High-throughput

0.479

High

934824

H31
Histone H3.1

1

11

High-throughput

0.479

High

998787

EP300
Histone acetyltransferase p300

1

10

High-throughput

0.479

High

1022110

NFX1
Transcriptional repressor NF-X1

1

9

High-throughput

0.479

High

1029488

TIF1B
Transcription intermediary factor 1-beta

1

15

High-throughput

0.479

High

1030085

DHRS2
Dehydrogenase/reductase SDR family member 2, mitochondrial

1

1

High-throughput

0.479

High

1030273

G3BP1
Ras GTPase-activating protein-binding protein 1

1

8

High-throughput

0.479

High

1035797

BIRC3
Baculoviral IAP repeat-containing protein 3

1

6

High-throughput

0.479

High

1036622

SQSTM
Sequestosome-1

1

5

High-throughput

0.479

High

1040906

MTMR2
Myotubularin-related protein 2

1

3

High-throughput

0.479

High

1066196

KIF14
Kinesin-like protein KIF14

1

9

High-throughput

0.479

High

1081274

E2F4
Transcription factor E2F4

1

4

High-throughput

0.479

High

1082171

CSRP2
Cysteine and glycine-rich protein 2

1

3

High-throughput

0.479

High

1088085

UPP1
Uridine phosphorylase 1

1

1

High-throughput

0.479

High

1102996

DHX30
ATP-dependent RNA helicase DHX30

1

11

High-throughput

0.479

High

1102997

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

6

Small-scale

0.479

High

1102998

ZCH18
Zinc finger CCCH domain-containing protein 18

1

19

High-throughput

0.479

High

1102999

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

11

High-throughput

0.479

High

1103000

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

1

High-throughput

0.479

High

1103002

TNIP2
TNFAIP3-interacting protein 2

1

2

High-throughput

0.479

High

1103004

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

5

High-throughput

0.479

High

1103005

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1103006

RBP56
TATA-binding protein-associated factor 2N

1

11

High-throughput

0.479

High

1103011

DDRGK
DDRGK domain-containing protein 1

1

5

High-throughput

0.479

High

1103013

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1103016

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

2

High-throughput

0.479

High

1103017

ANM1
Protein arginine N-methyltransferase 1

1

6

High-throughput

0.479

High

1103018

RIOK1
Serine/threonine-protein kinase RIO1

1

4

High-throughput

0.479

High

1103019

TBB2B
Tubulin beta-2B chain

1

20

High-throughput

0.479

High

1103020

FACD2
Fanconi anemia group D2 protein

1

4

High-throughput

0.479

High

1103022

CCDC8
Coiled-coil domain-containing protein 8

1

2

Small-scale

0.479

High

1103026

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

5

High-throughput

0.479

High

1103027

RAD18
E3 ubiquitin-protein ligase RAD18

1

2

High-throughput

0.479

High

1103029

DJC17
DnaJ homolog subfamily C member 17

1

13

High-throughput

0.479

High

1103030

PEF1
Peflin

1

1

High-throughput

0.479

High

1103031

DIC
Mitochondrial dicarboxylate carrier

1

10

High-throughput

0.479

High

1103032

ZRAN1
Ubiquitin thioesterase ZRANB1

1

10

High-throughput

0.479

High

1103037

MTCH2
Mitochondrial carrier homolog 2

1

9

High-throughput

0.479

High

835182

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

1

High-throughput

0.470

High

1014229

MN1
Transcriptional activator MN1

1

0

Small-scale

0.458

High

1103008

FBX32
F-box only protein 32

1

0

High-throughput

0.458

High

1103012

RN157
E3 ubiquitin ligase RNF157

1

0

Small-scale

0.458

High

402100

JUN
Transcription factor Jun

1

14

High-throughput

0.445

High

853915

NCBP2
Nuclear cap-binding protein subunit 2

1

9

High-throughput

0.445

High

1047113

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

6

High-throughput

0.445

High

1075663

SF01
Splicing factor 1

1

4

High-throughput

0.445

High

1102989

NCBP3
Nuclear cap-binding protein subunit 3

1

1

High-throughput

0.445

High

1102990

ODFP2
Outer dense fiber protein 2

1

11

High-throughput

0.445

High

1103014

NUDC1
NudC domain-containing protein 1

1

1

High-throughput

0.445

High

197316

SERA
D-3-phosphoglycerate dehydrogenase

1

8

High-throughput

0.437

High

327181

TXD12
Thioredoxin domain-containing protein 12

1

3

High-throughput

0.437

High

390926

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.437

High

398358

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

20

High-throughput

0.437

High

636945

ATPA
ATP synthase subunit alpha, mitochondrial

1

5

High-throughput

0.437

High

682351

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

4

High-throughput

0.437

High

687223

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

3

High-throughput

0.437

High

827402

EFTU
Elongation factor Tu, mitochondrial

1

6

High-throughput

0.437

High

839605

SERPH
Serpin H1

1

4

High-throughput

0.437

High

873427

P5CS
Delta-1-pyrroline-5-carboxylate synthase

1

7

High-throughput

0.437

High

875980

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

5

High-throughput

0.437

High

1067723

PDIA6
Protein disulfide-isomerase A6

1

11

High-throughput

0.437

High

1102993

RICTR
Rapamycin-insensitive companion of mTOR

1

4

High-throughput

0.437

High

1102994

C1TM
Monofunctional C1-tetrahydrofolate synthase, mitochondrial

1

3

High-throughput

0.437

High

1103001

TXND5
Thioredoxin domain-containing protein 5

1

11

High-throughput

0.437

High

1103021

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.437

High

1103024

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

20

High-throughput

0.437

High

1103028

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

7

High-throughput

0.437

High

831384

CEBPA
CCAAT/enhancer-binding protein alpha

1

13

High-throughput

0.408

High

1102991

LITD1
LINE-1 type transposase domain-containing protein 1

1

2

High-throughput

0.407

High

63651

RASFA
Ras association domain-containing protein 10

2

0

High-throughput

0.316

High

1102988

MSS51
Putative protein MSS51 homolog, mitochondrial

2

0

High-throughput

0.316

High

281650

WFS1
Wolframin

1

0

High-throughput

0.268

Low

800233

ACDSB
Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial

1

0

High-throughput

0.249

Low

1103023

KT3K
Ketosamine-3-kinase

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024