Interactor 1: PTN11 (P35235)
Tyrosine-protein phosphatase non-receptor type 11 (EC 3.1.3.48) (Protein-tyrosine phosphatase SYP) (SH-PTP2) (SHP-2) (Shp2)
Gene: Ptpn11
Interactor 2: SHC1 (P98083)
SHC-transforming protein 1 (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9393882 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SH2~SH2, SH2~Y_phosphatase |
| Common GO terms | GO:0001784 - phosphotyrosine residue binding GO:0005158 - insulin receptor binding GO:0005829 - cytosol GO:0007173 - epidermal growth factor receptor signaling pathway GO:0030971 - receptor tyrosine kinase binding and 1 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
