HitPredict

Interactor 1: MERL (P35240)
Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomerlin) (Schwannomin)
Gene: NF2

Interactor 2: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26972000
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 595 Hs			1 832
+	Hs
		719616 MERL_HUMAN (1-595): 1.12e-172: 504: 100.00		Q9H4D1_HUMAN (1-832): 0: 697: 90.75
+	Hs
		883686 FARP1_HUMAN (2-526): 5.38e-114: 366: 18.35		RIPK4_HUMAN (1-832): 0: 726: 100.00
+	Hs
		883679 E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04		RIPK4_HUMAN (1-832): 0: 726: 100.00
+	Hs
		299252 FARP2_HUMAN (3-537): 6.42e-112: 360: 17.89		RIPK4_HUMAN (1-832): 0: 726: 100.00
+	Hs
		1330900 FARP1_HUMAN (2-526): 5.38e-114: 366: 18.35		Q9H4D1_HUMAN (1-832): 0: 697: 90.75
+	Hs
		1330892 E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04		Q9H4D1_HUMAN (1-832): 0: 697: 90.75
+	Hs
		640287 PTN3_HUMAN (3-433): 3.81e-115: 366: 22.52		ANR50_HUMAN (353-788): 9.53e-101: 343: 24.36
+	Hs
		547010 EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20		ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89
+	Hs
		547272 EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20		KDIS_HUMAN (251-655): 7.94e-53: 202: 18.63
+	Hs
		201750 EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20		RIPK2_HUMAN (31-276): 6.59e-54: 197: 44.94
+	Hs
		547029 EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20		ANK3_HUMAN (659-832): 4.77e-45: 178: 32.57
+	Hs
		965179 FARP1_HUMAN (2-526): 5.38e-114: 366: 18.35		ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89
+	Hs
		965178 E41L3_HUMAN (14-484): 8.79e-113: 363: 21.04		ANK2_HUMAN (592-832): 1.31e-65: 241: 27.89
+	Hs
		1336475 E41LA_HUMAN (19-416): 3.96e-121: 375: 24.46		KDIS_HUMAN (251-655): 7.94e-53: 202: 18.63
+	Hs
		640286 PTN3_HUMAN (3-433): 3.81e-115: 366: 22.52		KDIS_HUMAN (251-655): 7.94e-53: 202: 18.63
+	Hs
		1021466 E41LA_HUMAN (19-416): 3.96e-121: 375: 24.46		ANK3_HUMAN (659-832): 4.77e-45: 178: 32.57
+	Hs
		1021479 FARP1_HUMAN (2-526): 5.38e-114: 366: 18.35		ANK3_HUMAN (659-832): 4.77e-45: 178: 32.57
+	Hs
		166880 EZRI_HUMAN (19-595): 8.21e-152: 450: 44.20		ANR28_HUMAN (252-539): 5.33e-14: 78.4: 10.62
+	Hs
		257705 E41L5_HUMAN (2-595): 6.77e-134: 410: 18.38		ANR17_HUMAN (384-541): 2.36e-20: 99.6: 14.47
+	Hs
		1219853 E41L5_HUMAN (2-595): 6.77e-134: 410: 18.38		ANKH1_HUMAN (384-541): 3.69e-19: 95.3: 14.47