Protein: CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial (PPIase C) (EC 5.2.1.8) (Cyclophilin C) (PPI-III) (Rotamase C)

Gene: CYPC, CPR3
Organism: Saccharomyces cerevisiae S288C
Interactions: 85
UniProt ID: P25719

Gene Ontology (top 5):
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006457 - protein folding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

517922

SSBP1
Single-stranded nucleic acid-binding protein

1

7

High-throughput

0.647

High

680582

TEM1
Protein TEM1

1

3

High-throughput

0.618

High

680566

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

13

High-throughput

0.618

High

680585

XDJ1
DnaJ protein homolog XDJ1

1

1

High-throughput

0.618

High

604912

MDHM
Malate dehydrogenase, mitochondrial

2

4

High-throughput

0.584

High

680567

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

2

1

High-throughput

0.584

High

680575

MIC60
MICOS complex subunit MIC60

2

0

High-throughput

0.559

High

574558

YAK1
Dual specificity protein kinase YAK1

1

5

High-throughput

0.501

High

680618

GDE
Glycogen debranching enzyme

1

0

High-throughput

0.493

High

366952

ATPB
ATP synthase subunit beta, mitochondrial

1

5

High-throughput

0.479

High

448656

SNF1
Carbon catabolite-derepressing protein kinase

1

1

High-throughput

0.479

High

453256

QCR2
Cytochrome b-c1 complex subunit 2, mitochondrial

1

2

High-throughput

0.479

High

481511

HSP73
Heat shock protein SSA3

1

10

High-throughput

0.479

High

510247

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.479

High

578946

HSC82
ATP-dependent molecular chaperone HSC82

1

11

High-throughput

0.479

High

594892

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

619331

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.479

High

622326

ACON
Aconitate hydratase, mitochondrial

1

2

High-throughput

0.479

High

645692

HSP74
Heat shock protein SSA4

1

10

High-throughput

0.479

High

646316

RAD53
Serine/threonine-protein kinase RAD53

1

2

High-throughput

0.479

High

667157

CG24
G2/mitotic-specific cyclin-4

1

4

High-throughput

0.479

High

680569

SWC3
SWR1-complex protein 3

1

1

High-throughput

0.479

High

680570

HS104
Heat shock protein 104

1

1

Small-scale

0.479

High

680576

CDC27
Anaphase-promoting complex subunit CDC27

1

1

High-throughput

0.479

High

680577

ATG8
Autophagy-related protein 8

1

6

High-throughput

0.479

High

680581

CH10
10 kDa heat shock protein, mitochondrial

1

4

High-throughput

0.479

High

680584

PCF11
Protein PCF11

1

1

High-throughput

0.479

High

680593

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

7

High-throughput

0.479

High

680598

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

680606

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

680608

COX12
Cytochrome c oxidase subunit 12, mitochondrial

1

1

High-throughput

0.479

High

680613

VHS1
Serine/threonine-protein kinase VHS1

1

2

High-throughput

0.479

High

680614

POLH
DNA polymerase eta

1

1

High-throughput

0.479

High

680622

GYP1
GTPase-activating protein GYP1

1

1

High-throughput

0.479

High

677785

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

High-throughput

0.458

High

680572

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.458

High

680574

LTV1
Protein LTV1

1

0

High-throughput

0.458

High

680583

GDS1
GTPase-GDP dissociation stimulator BEM4

1

0

High-throughput

0.458

High

680586

GPB2
Guanine nucleotide-binding protein subunit beta 2

1

0

High-throughput

0.458

High

680588

KRE29
DNA repair protein KRE29

1

0

High-throughput

0.458

High

680589

AIM9
Altered inheritance of mitochondria protein 9, mitochondrial

1

0

High-throughput

0.458

High

680590

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.458

High

680597

STB1
Protein STB1

1

0

High-throughput

0.458

High

680601

MDM34
Mitochondrial distribution and morphology protein 34

1

0

High-throughput

0.458

High

680603

YBP2
YAP1-binding protein 2

1

0

High-throughput

0.458

High

680604

OGG1
N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase

1

0

High-throughput

0.458

High

680611

UME1
Transcriptional regulatory protein UME1

1

0

High-throughput

0.458

High

680612

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.458

High

680616

TYW2
tRNA wybutosine-synthesizing protein 2

1

0

High-throughput

0.458

High

680621

LDS2
Outer spore wall protein LDS2

1

0

High-throughput

0.458

High

680623

AB140
tRNA(Thr)

1

0

High-throughput

0.458

High

680627

CSN10
COP9 signalosome complex subunit 10

1

0

High-throughput

0.458

High

392323

HSP82
ATP-dependent molecular chaperone HSP82

1

11

High-throughput

0.445

High

523213

HSP71
Heat shock protein SSA1

1

10

High-throughput

0.445

High

526054

HSP72
Heat shock protein SSA2

1

10

High-throughput

0.445

High

543998

SSB1
Ribosome-associated molecular chaperone SSB1

1

9

High-throughput

0.445

High

680571

HSP7F
Heat shock protein homolog SSE1

1

12

High-throughput

0.445

High

402713

ARLY
Argininosuccinate lyase

1

2

High-throughput

0.437

High

680568

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

680580

AP18A
Clathrin coat assembly protein AP180A

1

1

High-throughput

0.437

High

680594

FKH2
Fork head protein homolog 2

1

3

High-throughput

0.437

High

680596

PFS2
Polyadenylation factor subunit 2

1

6

High-throughput

0.437

High

680599

RSSA2
Small ribosomal subunit protein uS2B

1

2

High-throughput

0.437

High

680605

DBP6
ATP-dependent RNA helicase DBP6

1

5

High-throughput

0.437

High

680610

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

3

High-throughput

0.437

High

680625

YTM1
Ribosome biogenesis protein YTM1

1

5

High-throughput

0.437

High

680626

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.437

High

680609

UBC7
Ubiquitin-conjugating enzyme E2 7

1

3

High-throughput

0.417

High

479966

PRTB
Cerevisin

1

0

High-throughput

0.249

Low

680573

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

680578

BRL1
Nucleus export protein BRL1

1

0

High-throughput

0.249

Low

680579

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.249

Low

680587

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.249

Low

680591

TGL3
Triacylglycerol lipase 3

1

0

High-throughput

0.249

Low

680592

RIC1
Guanine nucleotide exchange factor subunit RIC1

1

0

High-throughput

0.249

Low

680595

FIG4
Polyphosphoinositide phosphatase

1

0

High-throughput

0.249

Low

680600

SUM1
Suppressor of mar1-1 protein

1

0

High-throughput

0.249

Low

680602

NSA1
Ribosome biogenesis protein NSA1

1

0

High-throughput

0.249

Low

680607

ASI1
ERAD-associated E3 ubiquitin-protein ligase ASI1

1

0

High-throughput

0.249

Low

680615

TR120
Trafficking protein particle complex II-specific subunit 120

1

0

High-throughput

0.249

Low

680617

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

High-throughput

0.249

Low

680619

VAC14
Vacuole morphology and inheritance protein 14

1

0

High-throughput

0.249

Low

680620

RCL1
rRNA processing protein RCL1

1

0

High-throughput

0.249

Low

680624

SSP2
Sporulation-specific protein 2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025