HitPredict

Interactor 1: RADI (P35241)
Radixin
Gene: RDX

Interactor 2: SPTN1 (Q13813)
Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit)
Gene: SPTAN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005886 - plasma membrane GO:0030864 - cortical actin cytoskeleton GO:0045296 - cadherin binding GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 583 Hs			1 2472
+	Hs
		547044 EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Hs
		640097 MOES_HUMAN (1-583): 2.8e-161: 474: 80.96		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Hs
		505631 EPB41_HUMAN (3-553): 1.19e-125: 392: 20.48		SPTN1_HUMAN (1-2472): 0: 714: 100.00
+	Hs
		360610 EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28		SPTA1_HUMAN (1-2472): 2.98e-159: 552: 54.81
+	Dm
		574805 MOEH_DROME (2-583): 1.27e-147: 439: 58.29		ACTN_DROME (1864-2470): 1.19e-77: 281: 30.27
+	Hs
		297816 RADI_HUMAN (1-583): 3.49e-166: 487: 100.00		K0754_HUMAN (1-1482): 9.32e-58: 225: 14.65
+	Hs
		547057 EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28		GOGB1_HUMAN (2-1186): 3.65e-38: 160: 10.57
+	Hs
		547015 EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28		DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59
+	Hs
		719702 RADI_HUMAN (1-583): 3.49e-166: 487: 100.00		DYST_HUMAN (5-2410): 1.41e-35: 152: 10.59
+	Hs
		640102 MOES_HUMAN (1-583): 2.8e-161: 474: 80.96		GOGB1_HUMAN (2-1186): 3.65e-38: 160: 10.57
+	Hs
		719451 MERL_HUMAN (2-583): 1.72e-151: 450: 45.30		SPTB2_HUMAN (2-1043): 1.4e-42: 174: 20.52
+	Hs
		547281 EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28		MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48
+	Hs
		719790 RADI_HUMAN (1-583): 3.49e-166: 487: 100.00		MACF1_HUMAN (9-1261): 9.1e-18: 93.6: 12.48
+	Hs
		719681 RADI_HUMAN (1-583): 3.49e-166: 487: 100.00		CENPF_HUMAN (1723-2444): 8.12e-13: 77: 9.28
+	Hs
		521459 EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28		ACTN1_HUMAN (1862-2210): 3.16e-11: 71.2: 22.25
+	Hs
		211486 EZRI_HUMAN (1-583): 3.17e-166: 487: 76.28		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15
+	Hs
		211512 RADI_HUMAN (1-583): 3.49e-166: 487: 100.00		ACTN4_HUMAN (1843-2219): 1.15e-09: 66.2: 20.15
+	Hs
		640146 MOES_HUMAN (1-583): 2.8e-161: 474: 80.96		CP250_HUMAN (1768-2439): 4.39e-10: 67.7: 8.94
+	Dm
		1098248 MERH_DROME (3-583): 1.81e-130: 397: 40.26		Q7KV70_DROME (1-592): 1.99e-24: 115: 29.61
+	Hs
		505537 EPB41_HUMAN (3-553): 1.19e-125: 392: 20.48		SPTB1_HUMAN (1743-2409): 3.32e-13: 78.1: 19.70