HitPredict

Interactor 1: B3KSH4 (B3KSH4)
Huntingtin interacting protein 2, isoform CRA_a (cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa)
Gene: HIP2

Interactor 2: BIRC7 (Q96CA5)
Baculoviral IAP repeat-containing protein 7 (EC 2.3.2.27) (Kidney inhibitor of apoptosis protein) (KIAP) (Livin) (Melanoma inhibitor of apoptosis protein) (ML-IAP) (RING finger protein 50) (RING-type E3 ubiquitin transferase BIRC7) [Cleaved into: Baculoviral IAP repeat-containing protein 7 30kDa subunit (Truncated livin) (p30-Livin) (tLivin)]
Gene: BIRC7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19549727
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 97 Hs			1 298
+	Hs
		896349 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		BIRC7_HUMAN (1-298): 4.39e-104: 307: 100.00
+	Hs
		919817 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		BIRC7_HUMAN (1-298): 4.39e-104: 307: 100.00
+	At
		715121 UBC8_ARATH (1-52): 1.23e-29: 104: 38.46		RGLG3_ARATH (137-296): 4.74e-28: 112: 22.16
+	Hs
		919803 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		MYLIP_HUMAN (152-297): 3.79e-26: 108: 22.45
+	At
		715125 UBC8_ARATH (1-52): 1.23e-29: 104: 38.46		RGLG4_ARATH (137-296): 5.99e-25: 105: 20.37
+	Hs
		919818 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RSPRY_HUMAN (133-294): 1.51e-23: 102: 19.51
+	Hs
		919813 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		MIB2_HUMAN (236-297): 7.71e-23: 100: 38.71
+	Dm
		639392 UBCD1_DROME (1-51): 1.57e-29: 104: 39.22		DIAP1_DROME (77-253): 8.76e-22: 96.6: 20.23
+	Hs
		919721 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		BIRC3_HUMAN (240-298): 5.43e-20: 92: 71.67
+	Hs
		919776 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		MIB1_HUMAN (206-296): 7.37e-20: 91.6: 25.28
+	Hs
		896319 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		Q6PIA0_HUMAN (1-91): 4.23e-17: 80.4: 17.20
+	Hs
		896357 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		BIRC8_HUMAN (1-96): 5.33e-17: 80.4: 18.18
+	Hs
		895787 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		BIRC3_HUMAN (240-298): 5.43e-20: 92: 71.67
+	Hs
		919722 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		BIRC2_HUMAN (84-281): 4.95e-19: 88.9: 23.23
+	Hs
		895841 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		MIB1_HUMAN (206-296): 7.37e-20: 91.6: 25.28
+	Hs
		72153 B3KSH4_HUMAN (1-97): 7.05e-34: 113: 100.00		BIRC8_HUMAN (1-96): 5.33e-17: 80.4: 18.18
+	Hs
		895788 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		BIRC2_HUMAN (84-281): 4.95e-19: 88.9: 23.23
+	Hs
		919831 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		BIRC8_HUMAN (1-96): 5.33e-17: 80.4: 18.18
+	Hs
		919707 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		XIAP_HUMAN (1-96): 3.35e-13: 71.5: 19.19
+	Hs
		895777 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		XIAP_HUMAN (1-96): 3.35e-13: 71.5: 19.19