Protein: HRP1
Nuclear polyadenylated RNA-binding protein 4 (Cleavage factor IB) (CFIB) (Heterogeneous nuclear ribonucleoprotein 1)

Gene: HRP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 91
UniProt ID: Q99383

Gene Ontology (top 5):
GO:0000184 - nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

671464

RNA15
mRNA 3'-end-processing protein RNA15

3

20

Small-scale

0.837

High

796138

IMB2
Importin subunit beta-2

10

7

Small-scale

0.757

High

1031086

NOP3
Serine/arginine

2

20

Small-scale

0.754

High

793028

ANM1
Protein arginine N-methyltransferase 1

6

14

Small-scale

0.731

High

738952

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

4

1

Small-scale

0.693

High

448878

STE7
Serine/threonine-protein kinase STE7

1

9

High-throughput

0.691

High

737979

HOG1
Mitogen-activated protein kinase HOG1

1

10

High-throughput

0.691

High

738081

MKK2
MAP kinase kinase MKK2/SSP33

1

11

High-throughput

0.691

High

809108

DUN1
DNA damage response protein kinase DUN1

1

6

High-throughput

0.691

High

864447

IKS1
Probable serine/threonine-protein kinase IKS1

1

11

High-throughput

0.691

High

1027310

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

10

High-throughput

0.691

High

671437

RNA14
mRNA 3'-end-processing protein RNA14

4

3

Small-scale

0.690

High

602717

PHO85
Cyclin-dependent protein kinase PHO85

1

8

High-throughput

0.647

High

656694

KC11
Casein kinase I homolog 1

1

4

High-throughput

0.647

High

917228

ATG1
Serine/threonine-protein kinase ATG1

1

4

High-throughput

0.647

High

1404050

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

19

Small-scale

0.647

High

708691

TF2B
Transcription initiation factor IIB

3

2

Small-scale

0.640

High

721680

RENT1
ATP-dependent helicase NAM7

2

9

Small-scale

0.634

High

525731

HSP71
Heat shock protein SSA1

3

10

High-throughput

0.633

High

722401

XPO1
Exportin-1

1

10

Small-scale

0.621

High

757566

NCBP1
Nuclear cap-binding protein complex subunit 1

1

7

Small-scale

0.618

High

866146

JHD2
Histone demethylase JHD2

1

2

Small-scale

0.618

High

644710

AEP2
ATPase expression protein 2, mitochondrial

2

1

High-throughput

0.588

High

1059267

TSR1
Ribosome biogenesis protein TSR1

2

1

High-throughput

0.588

High

393607

HSP82
ATP-dependent molecular chaperone HSP82

2

4

High-throughput

0.584

High

1037970

NU100
Nucleoporin NUP100/NSP100

2

8

Small-scale

0.584

High

1053585

ISR1
Serine/threonine-protein kinase ISR1

1

0

High-throughput

0.578

High

403721

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

19

High-throughput

0.575

High

432753

RL7A
Large ribosomal subunit protein uL30A

1

6

High-throughput

0.575

High

676785

GBP2
Serine/arginine

1

20

High-throughput

0.575

High

455603

SYSC
Serine--tRNA ligase, cytoplasmic

2

0

High-throughput

0.563

High

1403996

MEX67
mRNA export factor MEX67

1

3

Small-scale

0.561

High

150041

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.536

High

427503

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

825311

MOB1
DBF2 kinase activator protein MOB1

1

0

High-throughput

0.513

High

694679

SPT5
Transcription elongation factor SPT5

1

3

Small-scale

0.501

High

511886

RS24A
Small ribosomal subunit protein eS24A

1

2

High-throughput

0.489

High

673140

RNQ1
[PIN+] prion protein RNQ1

1

0

High-throughput

0.486

High

477659

MYO1
Myosin-1

1

1

Small-scale

0.481

High

382441

H4
Histone H4

1

7

High-throughput

0.479

High

438174

NOT2
General negative regulator of transcription subunit 2

1

4

Small-scale

0.479

High

577590

CYC8
General transcriptional corepressor CYC8

1

12

Small-scale

0.479

High

594668

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

603129

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.479

High

671300

SIS1
Protein SIS1

1

2

High-throughput

0.479

High

679017

NOT1
General negative regulator of transcription subunit 1

1

1

Small-scale

0.479

High

680216

CDC48
Cell division control protein 48

1

7

High-throughput

0.479

High

726256

CCR4
CCR4-Not complex 3'-5'-exoribonuclease subunit Ccr4

1

6

Small-scale

0.479

High

745932

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

2

High-throughput

0.479

High

761148

NOT4
General negative regulator of transcription subunit 4

1

2

Small-scale

0.479

High

776687

DEF1
RNA polymerase II degradation factor 1

1

8

High-throughput

0.479

High

809071

POP2
Poly(A) ribonuclease POP2

1

3

Small-scale

0.479

High

826984

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

850297

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

7

High-throughput

0.479

High

924211

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

6

High-throughput

0.479

High

1036944

MLP1
Protein MLP1

1

14

Small-scale

0.479

High

1038014

NU116
Nucleoporin NUP116/NSP116

1

8

High-throughput

0.479

High

1044958

SYF1
Pre-mRNA-splicing factor SYF1

1

5

Small-scale

0.479

High

1054034

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

1054890

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

1084482

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

1084739

SMT3
Ubiquitin-like protein SMT3

1

2

High-throughput

0.479

High

1084872

DBP10
ATP-dependent RNA helicase DBP10

1

13

High-throughput

0.479

High

1085020

CMR1
DNA damage-binding protein CMR1

1

19

High-throughput

0.479

High

1085025

NOT5
General negative regulator of transcription subunit 5

1

2

Small-scale

0.479

High

735252

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

758058

MTR2
mRNA transport regulator MTR2

1

0

Small-scale

0.458

High

804885

NMD2
Nonsense-mediated mRNA decay protein 2

1

0

Small-scale

0.458

High

808944

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

1044877

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

1084289

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.458

High

776508

MPE1
Protein MPE1

1

1

High-throughput

0.457

High

802124

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.445

High

820271

SSB2
Ribosome-associated molecular chaperone SSB2

1

11

High-throughput

0.445

High

672481

STE50
Protein STE50

1

0

High-throughput

0.438

High

513309

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

513930

RS11B
Small ribosomal subunit protein uS17B

1

1

High-throughput

0.437

High

554657

RM02
Large ribosomal subunit protein bL27m

1

2

High-throughput

0.437

High

784202

RM24
Large ribosomal subunit protein bL28m

1

1

High-throughput

0.437

High

784371

RM17
Large ribosomal subunit protein mL46

1

1

High-throughput

0.437

High

784524

RM40
Large ribosomal subunit protein uL24m

1

1

High-throughput

0.437

High

812819

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

924307

RM22
Large ribosomal subunit protein uL22m

1

1

High-throughput

0.437

High

1056482

RM35
Large ribosomal subunit protein mL38

1

1

High-throughput

0.437

High

753681

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.407

High

738134

AEP1
ATPase expression protein 1, mitochondrial

2

0

High-throughput

0.324

High

894345

ATP22
Mitochondrial translation factor ATP22

2

0

High-throughput

0.307

High

748601

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

1042509

PEX29
Peroxisomal membrane protein PEX29

1

0

Small-scale

0.249

Low

1054062

PEX30
Peroxisomal membrane protein PEX30

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025