HitPredict

Interactor 1: ADA1A (P35348)
Alpha-1A adrenergic receptor (Alpha-1A adrenoreceptor) (Alpha-1A adrenoceptor) (Alpha-1C adrenergic receptor) (Alpha-adrenergic receptor 1c)
Gene: ADRA1A

Interactor 2: ADA1B (P35368)
Alpha-1B adrenergic receptor (Alpha-1B adrenoreceptor) (Alpha-1B adrenoceptor)
Gene: ADRA1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.806

The method score is based on:

Property Details
Experiments 12888550, 14645668
Identification Methods fluorescent resonance energy transfer, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~7tm_1
Common GO terms GO:0001996 - positive regulation of heart rate by epinephrine-norepinephrine
GO:0004937 - alpha1-adrenergic receptor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
and 11 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 466
Hs

1 520
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Last updated: 15 Jul 2024