Interactor 1: FBN2 (P35556)
Fibrillin-2 [Cleaved into: Placensin]
Gene: FBN2
Interactor 2: LTBP1 (Q14766)
Latent-transforming growth factor beta-binding protein 1 (LTBP-1) (Transforming growth factor beta-1-binding protein 1) (TGF-beta1-BP-1)
Gene: LTBP1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12429738 |
| Identification Methods | far western blotting, enzyme linked immunosorbent assay |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EGF_3~EGF_CA, EGF_CA~EGF_CA, EGF_CA~TB, EGF_CA~FXa_inhibition |
| Common GO terms | GO:0001527 - microfibril GO:0005509 - calcium ion binding GO:0005576 - extracellular region GO:0031012 - extracellular matrix GO:0035583 - sequestering of TGFbeta in extracellular matrix and 1 others more... |
| Homologous interactions | 17 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
