HitPredict

Interactor 1: FBN2 (P35556)
Fibrillin-2 [Cleaved into: Placensin]
Gene: FBN2

Interactor 2: ST14 (Q9Y5Y6)
Suppressor of tumorigenicity 14 protein (EC 3.4.21.109) (Matriptase) (Membrane-type serine protease 1) (MT-SP1) (Prostamin) (Serine protease 14) (Serine protease TADG-15) (Tumor-associated differentially-expressed gene 15 protein)
Gene: ST14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CUB~EGF_CA, CUB~FXa_inhibition, FXa_inhibition~Ldl_recept_a, FXa_inhibition~Trypsin
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2912 Hs			1 855
+	Hs
		371464 FBN2_HUMAN (1-2912): 0: 1400: 100.00		KLKB1_HUMAN (594-853): 1.1e-45: 176: 38.43
+	Hs
		724360 FBN1_HUMAN (1742-2819): 1.44e-54: 214: 21.20		ST14_HUMAN (1-855): 0: 715: 100.00
+	Hs
		1357254 NOTC3_HUMAN (8-486): 1.74e-24: 115: 14.18		ST14_HUMAN (1-855): 0: 715: 100.00
+	Hs
		1376965 JAG2_HUMAN (2-291): 1.2e-19: 99.3: 17.43		ST14_HUMAN (1-855): 0: 715: 100.00
+	Hs
		980582 NOTC2_HUMAN (2615-2838): 8.38e-12: 73.9: 14.04		ST14_HUMAN (1-855): 0: 715: 100.00
+	Hs
		612917 FBLN1_HUMAN (248-360): 4.28e-10: 67.4: 40.87		ST14_HUMAN (1-855): 0: 715: 100.00
+	Hs
		1354456 FBLN5_HUMAN (1500-1764): 6.93e-10: 66.2: 29.23		ST14_HUMAN (1-855): 0: 715: 100.00
+	Hs
		1198224 JAG2_HUMAN (2-291): 1.2e-19: 99.3: 17.43		TM11B_HUMAN (597-855): 2.3e-81: 269: 34.87
+	Hs
		1345092 JAG2_HUMAN (2-291): 1.2e-19: 99.3: 17.43		TMPS4_HUMAN (492-852): 2.39e-72: 246: 26.68
+	Hs
		980428 NOTC2_HUMAN (2615-2838): 8.38e-12: 73.9: 14.04		TM11B_HUMAN (597-855): 2.3e-81: 269: 34.87
+	Hs
		409496 FBLN1_HUMAN (248-360): 4.28e-10: 67.4: 40.87		HEPS_HUMAN (567-853): 7.02e-71: 241: 32.89