Interactor 1: HXK4 (P35557)
Hexokinase-4 (HK4) (EC 2.7.1.1) (Glucokinase) (Hexokinase type IV) (HK IV) (Hexokinase-D)
Gene: GCK

Interactor 2: GCKR (Q14397)
Glucokinase regulatory protein (GKRP) (Glucokinase regulator)
Gene: GCKR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.736

The method score is based on:

Property Details
Experiments 26620281, 22038520, 32296183, 10601273, unassigned1304, 11522786
Identification Methods affinity chromatography technology, pull down, fluorescent resonance energy transfer, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, enzyme linked immunosorbent assay, phage display
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0009749 - response to glucose
GO:0042593 - glucose homeostasis
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 465
Hs

1 625
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024