Protein: WDR5
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein) (WD repeat-containing protein BIG-3)

Gene: WDR5
Organism: Mus musculus
Interactions: 31
UniProt ID: P61965

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000123 - histone acetyltransferase complex
GO:0001501 - skeletal system development
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

965396

RBBP5
Retinoblastoma-binding protein 5

6

18

Small-scale

0.717

High

629214

PO5F1
POU domain, class 5, transcription factor 1

3

3

Small-scale

0.667

High

965403

RING2
E3 ubiquitin-protein ligase RING2

2

16

Small-scale

0.611

High

921223

CEBPA
CCAAT/enhancer-binding protein alpha

2

14

Small-scale

0.594

High

965405

KAT2A
Histone acetyltransferase KAT2A

2

17

Small-scale

0.571

High

965388

NR0B1
Nuclear receptor subfamily 0 group B member 1

1

20

High-throughput

0.554

High

965386

TF2L1
Transcription factor CP2-like protein 1

1

1

High-throughput

0.536

High

965390

ERR2
Steroid hormone receptor ERR2

1

17

High-throughput

0.536

High

965394

PHF20
PHD finger protein 20

1

12

Small-scale

0.536

High

965397

SALL4
Sal-like protein 4

1

1

High-throughput

0.536

High

312582

MEN1
Menin

1

5

Small-scale

0.479

High

662956

MDM2
E3 ubiquitin-protein ligase Mdm2

1

2

Small-scale

0.479

High

866404

PAX7
Paired box protein Pax-7

1

1

Small-scale

0.479

High

947423

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

1

Small-scale

0.479

High

965384

NFE2
Transcription factor NF-E2 45 kDa subunit

1

6

Small-scale

0.479

High

965385

Q3UM65
Runt-related transcription factor

1

1

Small-scale

0.479

High

965389

CTCF
Transcriptional repressor CTCF

1

2

Small-scale

0.479

High

965391

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

6

High-throughput

0.479

High

965393

KDM2B
Lysine-specific demethylase 2B

1

10

Small-scale

0.479

High

965398

MAFA
Transcription factor MafA

1

6

Small-scale

0.479

High

965400

CSR2B
Cysteine-rich protein 2-binding protein

1

7

Small-scale

0.479

High

965401

ELF5
ETS-related transcription factor Elf-5

1

7

High-throughput

0.479

High

965402

MBIP1
MAP3K12-binding inhibitory protein 1

1

2

Small-scale

0.479

High

965406

CAF1A
Chromatin assembly factor 1 subunit A

1

13

High-throughput

0.479

High

476218

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

2

Small-scale

0.445

High

704106

MAX
Protein max

1

20

High-throughput

0.445

High

965392

PAXI1
PAX-interacting protein 1

1

14

Small-scale

0.445

High

965395

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

Small-scale

0.445

High

965399

TAD2A
Transcriptional adapter 2-alpha

1

9

High-throughput

0.445

High

965404

XPO7
Exportin-7

1

12

High-throughput

0.445

High

965387

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

4

High-throughput

0.437

High


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Last updated: 11Aug2025