HitPredict

Interactor 1: MYH10 (P35580)
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)
Gene: MYH10

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	20936779
Identification Methods	two hybrid, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1976 Hs			1 247
+	Hs
		725130 MYH10_HUMAN (1-1976): 0: 1106: 100.00		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Mm
		926804 MYH10_MOUSE (1-1976): 0: 1112: 99.09		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Hs
		728460 MYH11_HUMAN (805-1976): 1.82e-68: 259: 18.21		1433E_HUMAN (1-244): 2.02e-141: 398: 63.53
+	Hs
		728471 MYH11_HUMAN (805-1976): 1.82e-68: 259: 18.21		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		728466 MYH11_HUMAN (805-1976): 1.82e-68: 259: 18.21		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		927643 MYH2_HUMAN (930-1976): 4.58e-66: 251: 18.27		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		646685 MYH11_HUMAN (805-1976): 1.82e-68: 259: 18.21		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		724761 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		647370 MYH2_HUMAN (930-1976): 4.58e-66: 251: 18.27		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		646681 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		683875 MYH11_HUMAN (805-1976): 1.82e-68: 259: 18.21		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16
+	Mm
		926855 MYH9_MOUSE (963-1970): 1.32e-59: 230: 17.42		1433Z_MOUSE (2-245): 8.46e-109: 315: 74.59
+	Hs
		522602 MYH7_HUMAN (1239-1976): 2.42e-54: 212: 17.75		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		522590 MYH7_HUMAN (1239-1976): 2.42e-54: 212: 17.75		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		927644 MYH13_HUMAN (1274-1976): 3.3e-44: 179: 12.76		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		647371 MYH13_HUMAN (1274-1976): 3.3e-44: 179: 12.76		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		502907 MYH3_HUMAN (732-1493): 2.91e-36: 153: 14.60		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59