Protein: PCGF5
Polycomb group RING finger protein 5 (RING finger protein 159)

Gene: PCGF5
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q86SE9

Gene Ontology (top 5):
GO:0000805 - X chromosome
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005794 - Golgi apparatus
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1286257

RING2
E3 ubiquitin-protein ligase RING2

10

19

Small-scale

0.982

High

1055820

RING1
E3 ubiquitin-protein ligase RING1

9

19

High-throughput

0.977

High

1286245

RYBP
RING1 and YY1-binding protein

8

20

High-throughput

0.967

High

1286244

YAF2
YY1-associated factor 2

8

20

High-throughput

0.966

High

1286267

CBX8
Chromobox protein homolog 8

4

20

High-throughput

0.914

High

1250603

BCOR
BCL-6 corepressor

3

20

High-throughput

0.873

High

1286261

PCGF1
Polycomb group RING finger protein 1

2

19

High-throughput

0.793

High

129756

CBX4
E3 SUMO-protein ligase CBX4

2

20

High-throughput

0.789

High

1204615

BCORL
BCL-6 corepressor-like protein 1

2

19

High-throughput

0.789

High

338883

CBX6
Chromobox protein homolog 6

2

20

High-throughput

0.768

High

625469

CSK22
Casein kinase II subunit alpha'

11

20

High-throughput

0.758

High

997826

CSK21
Casein kinase II subunit alpha

10

20

High-throughput

0.757

High

995112

CSK2B
Casein kinase II subunit beta

8

9

High-throughput

0.748

High

1286251

AUTS2
Autism susceptibility gene 2 protein

6

20

Small-scale

0.737

High

1286266

FBRS
Probable fibrosin-1

6

20

High-throughput

0.669

High

964661

DCAF7
DDB1- and CUL4-associated factor 7

3

20

High-throughput

0.667

High

351393

CBX7
Chromobox protein homolog 7

1

20

High-throughput

0.647

High

957117

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

Small-scale

0.647

High

1286241

PCGF5
Polycomb group RING finger protein 5

1

19

Small-scale

0.647

High

1286243

PHC2
Polyhomeotic-like protein 2

2

20

High-throughput

0.631

High

765667

BMI1
Polycomb complex protein BMI-1

1

19

High-throughput

0.618

High

766099

PCGF2
Polycomb group RING finger protein 2

1

19

High-throughput

0.618

High

909336

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

20

Small-scale

0.618

High

1132208

CBX2
Chromobox protein homolog 2

1

20

High-throughput

0.618

High

1185916

PCGF3
Polycomb group RING finger protein 3

1

19

High-throughput

0.618

High

1286263

PCGF6
Polycomb group RING finger protein 6

1

19

High-throughput

0.618

High

1286254

ANM6
Protein arginine N-methyltransferase 6

1

3

High-throughput

0.573

High

1090752

TRAF2
TNF receptor-associated factor 2

1

18

High-throughput

0.573

High

1286268

FBSL
Fibrosin-1-like protein

2

20

High-throughput

0.558

High

1286264

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

19

High-throughput

0.541

High

415679

HSPB1
Heat shock protein beta-1

1

5

High-throughput

0.536

High

610745

TCPA
T-complex protein 1 subunit alpha

1

19

High-throughput

0.536

High

724597

S10A7
Protein S100-A7

1

17

High-throughput

0.536

High

868723

LEG7
Galectin-7

1

16

High-throughput

0.536

High

876044

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.536

High

899113

TCPQ
T-complex protein 1 subunit theta

1

20

High-throughput

0.536

High

899457

TCPD
T-complex protein 1 subunit delta

1

20

High-throughput

0.536

High

990422

1433Z
14-3-3 protein zeta/delta

1

18

High-throughput

0.536

High

1286255

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

8

High-throughput

0.536

High

1286259

KIF2C
Kinesin-like protein KIF2C

1

11

High-throughput

0.536

High

1286270

PLK2
Serine/threonine-protein kinase PLK2

1

7

High-throughput

0.536

High

705442

GRN
Progranulin

1

2

High-throughput

0.515

High

1286271

POLK
DNA polymerase kappa

1

0

High-throughput

0.513

High

821430

TCPZ
T-complex protein 1 subunit zeta

1

20

High-throughput

0.489

High

1007113

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.489

High

1229151

FRPD2
FERM and PDZ domain-containing protein 2

1

5

High-throughput

0.489

High

1286260

TCPH
T-complex protein 1 subunit eta

1

20

High-throughput

0.489

High

1286277

SNX9
Sorting nexin-9

1

5

High-throughput

0.489

High

1131064

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

12

High-throughput

0.481

High

1240443

DHX57
Putative ATP-dependent RNA helicase DHX57

1

8

High-throughput

0.481

High

1286256

QKI
KH domain-containing RNA-binding protein QKI

1

5

High-throughput

0.481

High

143085

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

173007

XPO1
Exportin-1

1

11

High-throughput

0.479

High

210039

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.479

High

225044

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.479

High

226565

TLX2
T-cell leukemia homeobox protein 2

1

10

High-throughput

0.479

High

272288

OBSL1
Obscurin-like protein 1

1

5

High-throughput

0.479

High

282742

E2F6
Transcription factor E2F6

1

15

High-throughput

0.479

High

289158

PRDM1
PR domain zinc finger protein 1

1

3

High-throughput

0.479

High

315738

RECQ4
ATP-dependent DNA helicase Q4

1

16

High-throughput

0.479

High

474095

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

538426

EGR2
E3 SUMO-protein ligase EGR2

1

7

High-throughput

0.479

High

636107

CD11B
Cyclin-dependent kinase 11B

1

13

High-throughput

0.479

High

662243

PAX7
Paired box protein Pax-7

1

20

High-throughput

0.479

High

662450

GATA2
Endothelial transcription factor GATA-2

1

16

High-throughput

0.479

High

685249

PAX6
Paired box protein Pax-6

1

18

High-throughput

0.479

High

725277

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.479

High

938467

PAX9
Paired box protein Pax-9

1

18

High-throughput

0.479

High

942444

GSC
Homeobox protein goosecoid

1

16

High-throughput

0.479

High

944693

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

965755

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

16

Small-scale

0.479

High

992236

SKP1
S-phase kinase-associated protein 1

1

10

High-throughput

0.479

High

1006854

PHC1
Polyhomeotic-like protein 1

1

20

High-throughput

0.479

High

1040057

PAX2
Paired box protein Pax-2

1

18

High-throughput

0.479

High

1056620

PAX8
Paired box protein Pax-8

1

18

High-throughput

0.479

High

1087835

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1097391

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.479

High

1103254

CTBP1
C-terminal-binding protein 1

1

8

High-throughput

0.479

High

1133499

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1197521

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

20

High-throughput

0.479

High

1286242

MGAP
MAX gene-associated protein

1

13

High-throughput

0.479

High

1286246

CBPC5
Cytosolic carboxypeptidase-like protein 5

1

2

High-throughput

0.479

High

1286247

PHC3
Polyhomeotic-like protein 3

1

20

High-throughput

0.479

High

1286248

CSK23
Casein kinase II subunit alpha 3

1

20

High-throughput

0.479

High

1286249

KDM2B
Lysine-specific demethylase 2B

1

20

High-throughput

0.479

High

1286250

SP7
Transcription factor Sp7

1

18

High-throughput

0.479

High

1286252

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

20

High-throughput

0.479

High

1286253

SCMH1
Polycomb protein SCMH1

1

20

High-throughput

0.479

High

1286258

FEV
Protein FEV

1

13

High-throughput

0.479

High

1286265

FOXQ1
Forkhead box protein Q1

1

8

High-throughput

0.479

High

1286269

4ET
Eukaryotic translation initiation factor 4E transporter

1

1

High-throughput

0.479

High

1286272

XPO7
Exportin-7

1

10

High-throughput

0.479

High

1286273

KLF15
Krueppel-like factor 15

1

20

High-throughput

0.479

High

1286274

CD11A
Cyclin-dependent kinase 11A

1

13

High-throughput

0.479

High

1286275

NISCH
Nischarin

1

2

High-throughput

0.479

High

1286276

MARF1
Meiosis regulator and mRNA stability factor 1

1

3

High-throughput

0.479

High

848790

MAGAA
Melanoma-associated antigen 10

1

10

High-throughput

0.445

High

365415

PGK1
Phosphoglycerate kinase 1

1

3

High-throughput

0.437

High

540044

BCR
Breakpoint cluster region protein

1

5

High-throughput

0.437

High

379265

IGHG1
Immunoglobulin heavy constant gamma 1

1

8

High-throughput

0.407

High

332665

LYPD3
Ly6/PLAUR domain-containing protein 3

1

0

High-throughput

0.279

Low

1286262

K1671
Uncharacterized protein KIAA1671

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025