HitPredict

Interactor 1: MYH10 (P35580)
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)
Gene: MYH10

Interactor 2: CYTSB (Q5M775)
Cytospin-B (Nuclear structure protein 5) (NSP5) (Sperm antigen HCMOGT-1) (Sperm antigen with calponin homology and coiled-coil domains 1)
Gene: SPECC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1976 Hs			1 1068
+	Hs
		725189 MYH10_HUMAN (1-1976): 0: 1106: 100.00		MYH14_HUMAN (366-799): 4.09e-49: 193: 20.33
+	Hs
		725095 MYH10_HUMAN (1-1976): 0: 1106: 100.00		MYH10_HUMAN (120-977): 3.57e-39: 161: 10.29
+	Hs
		724687 MYH10_HUMAN (1-1976): 0: 1106: 100.00		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		725097 MYH10_HUMAN (1-1976): 0: 1106: 100.00		MYH11_HUMAN (487-993): 4.15e-16: 86.1: 11.83
+	Hs
		724861 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		CYTSB_HUMAN (1-1068): 5.36e-72: 262: 100.00
+	Hs
		724895 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		MYH14_HUMAN (366-799): 4.09e-49: 193: 20.33
+	Hs
		521484 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		ACTN1_HUMAN (960-1067): 7.16e-33: 139: 40.37
+	Dm
		404218 MYSA_DROME (998-1976): 3.54e-63: 241: 18.51		ACTN_DROME (960-1067): 1.29e-33: 142: 36.70
+	Hs
		528432 MYH8_HUMAN (930-1976): 2.91e-65: 248: 17.93		MYH13_HUMAN (221-985): 2.46e-30: 132: 10.64
+	Hs
		724686 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		MYH9_HUMAN (34-584): 1.32e-23: 110: 9.16
+	Hs
		522657 MYH4_HUMAN (930-1976): 7.57e-64: 243: 17.51		MYH7_HUMAN (1-526): 4.38e-18: 92.6: 8.26
+	Hs
		528435 MYH8_HUMAN (930-1976): 2.91e-65: 248: 17.93		MYH4_HUMAN (2-423): 3.1e-15: 83.4: 9.93
+	Hs
		211515 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		ACTN4_HUMAN (963-1066): 6.3e-15: 81.6: 41.91
+	Hs
		724893 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		MICA3_HUMAN (956-1067): 2.33e-14: 80.5: 38.05
+	Hs
		502933 MYH4_HUMAN (930-1976): 7.57e-64: 243: 17.51		MYH3_HUMAN (453-992): 2.92e-15: 83.4: 10.89
+	Hs
		725035 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		MYO5C_HUMAN (47-496): 1.63e-12: 74.3: 10.21
+	Hs
		724873 MYH9_HUMAN (877-1976): 1.43e-64: 246: 17.95		CYTSA_HUMAN (1-389): 7.43e-11: 68.7: 7.36