HitPredict

Interactor 1: COPB2 (P35606)
Coatomer subunit beta' (Beta'-coat protein) (Beta'-COP) (p102)
Gene: COPB2

Interactor 2: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27684187, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 906 Hs			1 504
+	Hs
		725523 COPB2_HUMAN (1-906): 0: 736: 100.00		ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17
+	Hs
		725568 COPB2_HUMAN (1-906): 0: 736: 100.00		SMUF1_HUMAN (89-504): 7.79e-117: 363: 20.05
+	Hs
		725589 COPB2_HUMAN (1-906): 0: 736: 100.00		WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61
+	Hs
		808418 COPA_HUMAN (7-900): 1.24e-158: 498: 22.74		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Sc
		765291 COPB2_YEAST (3-841): 1.41e-165: 507: 43.87		RSP5_YEAST (3-504): 1.79e-105: 334: 15.25
+	Sc
		784416 COPB2_YEAST (3-841): 1.41e-165: 507: 43.87		TOM1_YEAST (261-504): 2.18e-46: 176: 11.34
+	Sc
		765342 COPA_YEAST (5-433): 5.89e-67: 245: 14.18		RSP5_YEAST (3-504): 1.79e-105: 334: 15.25
+	Hs
		125310 WDR5_HUMAN (553-670): 9.92e-20: 93.4: 8.94		WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54
+	Hs
		808450 WDR5_HUMAN (553-670): 9.92e-20: 93.4: 8.94		YAP1_HUMAN (1-504): 7.71e-118: 357: 100.00
+	Sc
		863628 COPA_YEAST (5-433): 5.89e-67: 245: 14.18		TOM1_YEAST (261-504): 2.18e-46: 176: 11.34