HitPredict

Interactor 1: ACTN2 (P35609)
Alpha-actinin-2 (Alpha-actinin skeletal muscle isoform 2) (F-actin cross-linking protein)
Gene: ACTN2

Interactor 2: PDLI3 (Q53GG5)
PDZ and LIM domain protein 3 (Actinin-associated LIM protein) (Alpha-actinin-2-associated LIM protein)
Gene: PDLIM3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.710

The method score is based on:

Property Details
Experiments 25416956, 25910212, 23414517, 31515488
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid bait and prey pooling approach, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0030018 - Z disc
GO:0030036 - actin cytoskeleton organization
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 894
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024