HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: RBM25 (P49756)
RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7)
Gene: RBM25

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29884807
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0008380 - RNA splicing
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 843
+	Hs
		833493 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		RBM25_HUMAN (1-843): 8.68e-63: 229: 100.00
+	Hs
		967233 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		NIPBL_HUMAN (3-760): 2.72e-54: 207: 10.34
+	Hs
		726962 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		PHF3_HUMAN (280-432): 6.42e-20: 98.1: 25.33
+	Hs
		703359 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		CSTF2_HUMAN (78-259): 3.07e-15: 81.8: 16.84
+	Hs
		1068620 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		PLEC_HUMAN (142-787): 2.15e-11: 70.2: 11.30
+	Hs
		725096 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		MYH10_HUMAN (228-817): 4.57e-14: 78.7: 9.49
+	Hs
		726862 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		GRDN_HUMAN (116-772): 9.29e-12: 71.4: 11.87
+	Hs
		726832 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		PLEC_HUMAN (142-787): 2.15e-11: 70.2: 11.30
+	Hs
		967422 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		CSTFT_HUMAN (76-170): 1.7e-15: 82.5: 29.17
+	Hs
		703370 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		CSTF2_HUMAN (78-259): 3.07e-15: 81.8: 16.84
+	Hs
		967188 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		PLEC_HUMAN (142-787): 2.15e-11: 70.2: 11.30