HitPredict

Interactor 1: FUS (P35637)
RNA-binding protein FUS (75 kDa DNA-pairing protein) (Oncogene FUS) (Oncogene TLS) (POMp75) (Translocated in liposarcoma protein)
Gene: FUS

Interactor 2: TF7L2 (Q9NQB0)
Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4)
Gene: TCF7L2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16230076
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 526 Hs			1 619
+	Hs
		967456 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		TF7L2_HUMAN (1-619): 4e-84: 277: 100.00
+	Hs
		967399 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		SOX7_HUMAN (317-610): 3.06e-44: 164: 18.27
+	Hs
		727730 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		SOX5_HUMAN (3-485): 3.95e-38: 152: 12.73
+	Hs
		996807 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		818317 RBP56_HUMAN (42-460): 2.62e-42: 161: 48.10		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		967374 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		CIC_HUMAN (43-578): 1.85e-33: 139: 15.01
+	Hs
		726648 FUS_HUMAN (1-526): 1.99e-39: 152: 100.00		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		817937 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		996959 PPIE_HUMAN (280-514): 1.23e-31: 125: 19.46		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		996982 RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		818665 RBM8A_HUMAN (219-366): 3.35e-27: 109: 26.35		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Mm
		818764 RBM8A_MOUSE (219-366): 3.35e-27: 109: 26.35		SOX2_MOUSE (318-613): 2.17e-26: 111: 14.15
+	Hs
		867119 SC24C_HUMAN (1-262): 5.36e-11: 67.4: 14.34		CIC_HUMAN (43-578): 1.85e-33: 139: 15.01
+	Hs
		967541 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		PCLO_HUMAN (20-610): 1.45e-09: 63.4: 9.22
+	Hs
		175773 EWS_HUMAN (3-451): 5.13e-31: 129: 31.05		HMGB3_HUMAN (354-438): 3.21e-09: 59.2: 17.24
+	Hs
		818011 PABP4_HUMAN (280-379): 4.96e-13: 73.5: 22.00		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69