HitPredict

Interactor 1: NU214 (P35658)
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)
Gene: NUP214

Interactor 2: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	23667531
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2090 Hs			1 317
+	Hs
		818668 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818382 MINT_HUMAN (283-1766): 1.23e-24: 115: 7.56		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Mm
		101612 F8VQL9_MOUSE (316-1903): 4.47e-20: 100: 9.63		Q60I23_MOUSE (1-317): 7.89e-75: 234: 96.24
+	Hs
		817913 MAP1A_HUMAN (300-1213): 1.74e-17: 92.2: 9.39		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818049 NCOA6_HUMAN (325-1617): 1.29e-17: 92.2: 8.74		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		577685 SON_HUMAN (277-1824): 2.67e-46: 186: 9.42		CIC_HUMAN (3-272): 8.9e-33: 130: 22.26
+	Mm
		818728 NUP98_MOUSE (1464-1973): 1.58e-16: 88.9: 16.03		SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67
+	Hs
		577625 SON_HUMAN (277-1824): 2.67e-46: 186: 9.42		SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68
+	Hs
		727832 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27
+	Hs
		1056996 MDC1_HUMAN (423-1348): 9.84e-37: 155: 10.01		TF7L2_HUMAN (14-255): 5.81e-35: 135: 19.75
+	Hs
		727830 PRC2C_HUMAN (355-2083): 2.49e-28: 127: 9.57		SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27
+	Hs
		331812 MDC1_HUMAN (423-1348): 9.84e-37: 155: 10.01		NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71
+	Hs
		1332335 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19
+	Hs
		881837 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42
+	Hs
		1311943 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		SOX7_HUMAN (23-299): 8.76e-34: 129: 27.03
+	Hs
		727951 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		SOX6_HUMAN (29-244): 2.42e-29: 120: 23.61
+	Hs
		225812 NCOR2_HUMAN (279-1978): 9.26e-33: 142: 8.93		SOX15_HUMAN (13-118): 1.78e-31: 119: 66.04
+	Hs
		727947 PRC2C_HUMAN (355-2083): 2.49e-28: 127: 9.57		SOX6_HUMAN (29-244): 2.42e-29: 120: 23.61
+	Hs
		818804 NCOA6_HUMAN (325-1617): 1.29e-17: 92.2: 8.74		SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57
+	Hs
		1057795 NCOA6_HUMAN (325-1617): 1.29e-17: 92.2: 8.74		SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19