Protein: DBP6
ATP-dependent RNA helicase DBP6 (EC 3.6.4.13) (DEAD box protein 6)

Gene: DBP6
Organism: Saccharomyces cerevisiae S288C
Interactions: 82
UniProt ID: P53734

Gene Ontology (top 5):
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000466 - maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

758237

URB1
Nucleolar pre-ribosomal-associated protein 1

7

2

Small-scale

0.748

High

865404

URB2
Nucleolar pre-ribosomal-associated protein 2

7

1

Small-scale

0.742

High

738234

NHP2
H/ACA ribonucleoprotein complex subunit NHP2

1

7

High-throughput

0.698

High

804860

NMD2
Nonsense-mediated mRNA decay protein 2

1

0

Small-scale

0.687

High

637252

PWP1
Periodic tryptophan protein 1

1

20

High-throughput

0.665

High

923025

RSA3
Ribosome assembly protein 3

4

0

Small-scale

0.643

High

923029

NOP8
60S ribosome subunit biogenesis protein NOP8

4

0

Small-scale

0.643

High

918934

PESC
Pescadillo homolog

3

7

Small-scale

0.640

High

923034

MAK21
Ribosome biogenesis protein MAK21

3

15

Small-scale

0.640

High

793507

MAK5
ATP-dependent RNA helicase MAK5

1

16

Small-scale

0.618

High

803897

CIC1
Proteasome-interacting protein CIC1

1

6

High-throughput

0.618

High

864487

MTR4
ATP-dependent RNA helicase DOB1

1

15

Small-scale

0.618

High

923021

DHR1
Probable ATP-dependent RNA helicase DHR1

1

14

High-throughput

0.618

High

545766

SSB1
Ribosome-associated molecular chaperone SSB1

2

15

High-throughput

0.601

High

780695

RRP14
Ribosomal RNA-processing protein 14

2

2

High-throughput

0.594

High

827566

RLP7
Ribosome biogenesis protein RLP7

2

14

High-throughput

0.594

High

849994

LOC1
60S ribosomal subunit assembly/export protein LOC1

2

2

High-throughput

0.594

High

923018

NOG2
Nucleolar GTP-binding protein 2

2

10

High-throughput

0.594

High

923032

RRS1
Regulator of ribosome biosynthesis

2

4

High-throughput

0.594

High

923017

DBP6
ATP-dependent RNA helicase DBP6

1

14

Small-scale

0.590

High

923027

DBP9
ATP-dependent RNA helicase DBP9

1

16

Small-scale

0.590

High

798277

ENP1
Essential nuclear protein 1

2

7

High-throughput

0.584

High

923038

NOP58
Nucleolar protein 58

2

12

High-throughput

0.584

High

154203

RL36B
Large ribosomal subunit protein eL36B

1

4

High-throughput

0.575

High

518352

IF4A
ATP-dependent RNA helicase eIF4A

1

17

High-throughput

0.575

High

527321

HSP72
Heat shock protein SSA2

2

14

High-throughput

0.552

High

722136

XPO1
Exportin-1

1

20

High-throughput

0.536

High

585327

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

6

High-throughput

0.515

High

677950

YCQ6
Uncharacterized protein YCR016W

1

1

High-throughput

0.515

High

923031

ESA1
Histone acetyltransferase ESA1

1

6

Small-scale

0.501

High

570092

RL3
Large ribosomal subunit protein uL3

1

6

High-throughput

0.479

High

672926

RRP43
Exosome complex component RRP43

1

3

High-throughput

0.479

High

707797

TF2B
Transcription initiation factor IIB

1

8

High-throughput

0.479

High

727221

HS104
Heat shock protein 104

1

5

High-throughput

0.479

High

735089

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

5

High-throughput

0.479

High

804639

SSF1
Ribosome biogenesis protein SSF1

1

6

High-throughput

0.479

High

814354

NOC2
Nucleolar complex protein 2

1

3

High-throughput

0.479

High

826712

DSN1
Kinetochore-associated protein DSN1

1

6

High-throughput

0.479

High

830149

NOP2
25S rRNA

1

12

Small-scale

0.479

High

844559

UTP10
U3 small nucleolar RNA-associated protein 10

1

6

High-throughput

0.479

High

923019

APJ1
J domain-containing protein APJ1

1

8

High-throughput

0.479

High

923022

UTP14
U3 small nucleolar RNA-associated protein 14

1

5

High-throughput

0.479

High

923026

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

4

High-throughput

0.479

High

923028

NOC4
Nucleolar complex protein 4

1

15

High-throughput

0.479

High

923030

SGO1
Shugoshin

1

6

High-throughput

0.479

High

923033

NOP53
Ribosome biogenesis protein NOP53

1

6

High-throughput

0.479

High

923035

RIO1
Serine/threonine-protein kinase RIO1

1

13

High-throughput

0.479

High

367086

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.445

High

382251

H4
Histone H4

1

9

High-throughput

0.445

High

524724

HSP71
Heat shock protein SSA1

1

14

High-throughput

0.445

High

579828

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.445

High

592407

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.445

High

603521

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.445

High

684799

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.445

High

742098

HSP7F
Heat shock protein homolog SSE1

1

19

High-throughput

0.445

High

752569

HSP78
Heat shock protein 78, mitochondrial

1

6

High-throughput

0.445

High

782396

RPF2
Ribosome biogenesis protein RPF2

1

4

High-throughput

0.445

High

819400

SSB2
Ribosome-associated molecular chaperone SSB2

1

15

High-throughput

0.445

High

823626

TCPE
T-complex protein 1 subunit epsilon

1

4

High-throughput

0.445

High

849536

GCN20
Protein GCN20

1

3

High-throughput

0.445

High

885039

RL4B
Large ribosomal subunit protein uL4B

1

8

High-throughput

0.445

High

923023

RRP5
rRNA biogenesis protein RRP5

1

12

High-throughput

0.445

High

923036

RL7B
Large ribosomal subunit protein uL30B

1

14

High-throughput

0.445

High

680605

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

5

High-throughput

0.437

High

748486

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

812532

LAA1
AP-1 accessory protein LAA1

1

7

High-throughput

0.437

High

918413

EIF2A
Eukaryotic translation initiation factor 2A

1

6

High-throughput

0.437

High

923020

NUM1
Nuclear migration protein NUM1

1

3

High-throughput

0.437

High

923037

CRM2
Homeostatic regulator of DAG

1

1

High-throughput

0.437

High

365136

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.426

High

439389

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.426

High

453719

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

486271

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

427386

RLA0
Large ribosomal subunit protein uL10

1

7

High-throughput

0.407

High

734163

EF2
Elongation factor 2

1

6

High-throughput

0.407

High

923024

PAL1
Protein PAL1

1

0

High-throughput

0.249

Low

358298

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

366059

CBPY
Carboxypeptidase Y

1

0

High-throughput

0.232

Low

386811

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

450623

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.232

Low

836819

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025