HitPredict

Interactor 1: NU214 (P35658)
Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)
Gene: NUP214

Interactor 2: RAN (P62826)
GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)
Gene: RAN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	28514442, 33961781, 35271311, 37516964
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006606 - protein import into nucleus and 1 others more... GO:0006611 - protein export from nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2090 Hs			1 216
+	Hs
		1070208 ITSN1_HUMAN (385-1370): 7.95e-65: 247: 14.42		RAB35_HUMAN (6-188): 1.31e-87: 258: 29.19
+	Hs
		914091 ITSN1_HUMAN (385-1370): 7.95e-65: 247: 14.42		RB11A_HUMAN (4-207): 7.68e-78: 234: 25.94
+	Hs
		297829 K0754_HUMAN (310-990): 1.34e-29: 132: 12.70		RAB35_HUMAN (6-188): 1.31e-87: 258: 29.19
+	Hs
		46903 A0A494C104_HUMAN (1120-1308): 3.06e-36: 139: 100.00		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		919232 MINT_HUMAN (283-1766): 1.23e-24: 115: 7.56		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		857959 NUP98_HUMAN (1481-1973): 9.16e-17: 89.7: 15.60		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		919191 TITIN_HUMAN (276-1124): 1.14e-10: 69.5: 8.16		RAN_HUMAN (1-216): 7.75e-79: 237: 100.00
+	Hs
		914253 TITIN_HUMAN (276-1124): 1.14e-10: 69.5: 8.16		RB11A_HUMAN (4-207): 7.68e-78: 234: 25.94
+	Hs
		592011 PTN23_HUMAN (547-1430): 4.5e-47: 189: 13.98		RAB4A_HUMAN (11-169): 1.53e-27: 105: 34.57