HitPredict

Interactor 1: HNF1B (P35680)
Hepatocyte nuclear factor 1-beta (HNF-1-beta) (HNF-1B) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2) (Variant hepatic nuclear factor 1) (vHNF1)
Gene: HNF1B

Interactor 2: PHS (P61457)
Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Dimerization cofactor of hepatocyte nuclear factor 1-alpha) (DCoH) (Dimerization cofactor of HNF1) (Phenylalanine hydroxylase-stimulating protein) (Pterin carbinolamine dehydratase) (PCD)
Gene: PCBD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.90	0.60	0.737

Property	Details
Experiments	27684187, 35140242, 32296183, 33961781, 20211142, unassigned1304
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 557 Hs			1 104
+	Mm
		655008 HNF1B_MOUSE (1-557): 1.16e-146: 435: 96.24		PHS_MOUSE (1-104): 3.02e-50: 155: 99.04
+	Hs
		727585 HNF1B_HUMAN (1-557): 6.73e-147: 436: 100.00		PHS2_HUMAN (1-103): 1.58e-46: 147: 61.17
+	Hs
		595917 HNF1A_HUMAN (1-551): 2.16e-85: 279: 53.21		PHS_HUMAN (1-104): 6.3e-50: 154: 100.00
+	Hs
		595955 HNF1A_HUMAN (1-551): 2.16e-85: 279: 53.21		PHS2_HUMAN (1-103): 1.58e-46: 147: 61.17
+	Mm
		607521 HNF1A_MOUSE (1-551): 3.98e-78: 260: 53.03		PHS_MOUSE (1-104): 3.02e-50: 155: 99.04
+	Mm
		607525 HNF1A_MOUSE (1-551): 3.98e-78: 260: 53.03		PHS2_MOUSE (1-103): 7.64e-49: 153: 66.02