HitPredict

Interactor 1: B4DET5 (B4DET5)
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121
Gene: B4DET5

Interactor 2: SEH1 (Q96EE3)
Nucleoporin SEH1 (GATOR2 complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein)
Gene: SEH1L

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005643 - nuclear pore
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 859 Hs			1 360
+	Hs
		65045 P121C_HUMAN (5-859): 6.37e-70: 253: 99.65		SEH1_HUMAN (1-360): 1.71e-77: 243: 100.00
+	Hs
		72754 B4DET5_HUMAN (1-859): 3.67e-72: 256: 100.00		SNR40_HUMAN (3-140): 3.35e-22: 98: 18.88
+	Hs
		1288235 P121A_HUMAN (5-859): 7.81e-63: 232: 96.73		SNR40_HUMAN (3-140): 3.35e-22: 98: 18.88
+	Hs
		858034 NUP98_HUMAN (354-817): 8.52e-16: 84.7: 20.71		SEH1_HUMAN (1-360): 1.71e-77: 243: 100.00
+	Hs
		878229 P121A_HUMAN (5-859): 7.81e-63: 232: 96.73		SEC13_HUMAN (216-346): 5.58e-17: 82.6: 18.80
+	Sp
		292982 NU189_SCHPO (572-840): 3.93e-10: 66.2: 24.78		SEC13_SCHPO (4-320): 6.36e-73: 230: 28.44
+	Hs
		1281391 PRR36_HUMAN (1-847): 1.59e-23: 109: 12.37		FBXW7_HUMAN (3-246): 5.14e-41: 154: 14.34
+	Hs
		1056932 MDC1_HUMAN (10-851): 1.63e-23: 109: 9.61		SNR40_HUMAN (3-140): 3.35e-22: 98: 18.88
+	Dm
		1370295 Q9VLS7_DROME (1-806): 4.3e-12: 72.5: 9.35		POC1_DROME (9-309): 3.76e-33: 128: 19.60
+	Hs
		903374 KMT2C_HUMAN (177-859): 7.96e-18: 91.3: 14.13		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Mm
		903669 KMT2C_MOUSE (84-825): 5.43e-16: 85.6: 9.49		WDR5_MOUSE (253-360): 5.88e-19: 88.4: 18.52
+	Hs
		857957 NUP98_HUMAN (354-817): 8.52e-16: 84.7: 20.71		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Hs
		857954 NUP98_HUMAN (354-817): 8.52e-16: 84.7: 20.71		SEC13_HUMAN (216-346): 5.58e-17: 82.6: 18.80
+	Dm
		1358850 NUP98_DROME (190-676): 3.73e-13: 75.9: 19.31		WDS_DROME (265-360): 3.21e-17: 83.7: 16.67
+	Hs
		903429 MBD6_HUMAN (6-603): 4.04e-11: 69: 11.22		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Hs
		903450 CIC_HUMAN (4-682): 1.05e-09: 64.7: 10.09		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Hs
		903345 Q86V38_HUMAN (223-856): 1.11e-09: 64.4: 10.17		WDR5_HUMAN (253-360): 5.88e-19: 88.4: 18.52
+	Sp
		1013470 NU189_SCHPO (572-840): 3.93e-10: 66.2: 24.78		SEH1_SCHPO (110-339): 1.59e-17: 84.3: 16.10
+	Hs
		878234 CIC_HUMAN (4-682): 1.05e-09: 64.7: 10.09		SEC13_HUMAN (216-346): 5.58e-17: 82.6: 18.80
+	Sc
		774364 NU159_YEAST (208-754): 4.31e-09: 62.8: 17.36		SEH1_YEAST (185-338): 3.3e-10: 62.7: 16.05