Protein: WDR46
WD repeat-containing protein 46 (WD repeat-containing protein BING4)

Gene: WDR46
Organism: Homo sapiens
Interactions: 187
UniProt ID: O15213

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0032040 - small-subunit processome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

182222

DKC1
H/ACA ribonucleoprotein complex subunit DKC1

2

4

High-throughput

0.789

High

182232

NSD2
Histone-lysine N-methyltransferase NSD2

2

18

High-throughput

0.789

High

182293

BOP1
Ribosome biogenesis protein BOP1

2

18

High-throughput

0.789

High

182300

WDR43
WD repeat-containing protein 43

2

19

High-throughput

0.789

High

182322

DHX30
ATP-dependent RNA helicase DHX30

2

13

High-throughput

0.789

High

182326

SPB1
pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3

2

10

High-throughput

0.789

High

182343

DDX27
Probable ATP-dependent RNA helicase DDX27

2

18

High-throughput

0.789

High

182364

DDX24
ATP-dependent RNA helicase DDX24

2

20

High-throughput

0.789

High

182368

YTDC2
3'-5' RNA helicase YTHDC2

2

14

High-throughput

0.789

High

182369

DDX31
ATP-dependent DNA helicase DDX31

2

19

High-throughput

0.789

High

182371

NMNA1
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1

2

1

High-throughput

0.789

High

182375

DDX21
Nucleolar RNA helicase 2

2

13

High-throughput

0.789

High

182350

TCPH
T-complex protein 1 subunit eta

2

20

High-throughput

0.705

High

182266

RL7A
Large ribosomal subunit protein eL8

1

9

High-throughput

0.691

High

182231

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

4

20

High-throughput

0.686

High

182282

CEBPZ
CCAAT/enhancer-binding protein zeta

3

3

High-throughput

0.656

High

182290

NOG2
Nucleolar GTP-binding protein 2

3

10

High-throughput

0.656

High

182363

REXO4
RNA exonuclease 4

3

3

High-throughput

0.656

High

182380

RBM28
RNA-binding protein 28

3

6

High-throughput

0.656

High

182298

RRS1
Ribosome biogenesis regulatory protein homolog

3

3

High-throughput

0.650

High

182393

RBMX2
RNA-binding motif protein, X-linked 2

3

14

High-throughput

0.650

High

182273

TCPB
T-complex protein 1 subunit beta

1

20

High-throughput

0.618

High

182356

H2AJ
Histone H2A.J

1

7

High-throughput

0.618

High

182256

TCPG
T-complex protein 1 subunit gamma

1

20

High-throughput

0.618

High

182271

H31
Histone H3.1

1

14

High-throughput

0.618

High

182277

H33
Histone H3.3

1

14

High-throughput

0.618

High

182284

DDX10
Probable ATP-dependent RNA helicase DDX10

1

20

High-throughput

0.618

High

182381

PK1IP
p21-activated protein kinase-interacting protein 1

1

18

High-throughput

0.618

High

182384

DDX56
Probable ATP-dependent RNA helicase DDX56

1

19

High-throughput

0.618

High

182385

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

11

High-throughput

0.618

High

182219

RRP8
Ribosomal RNA-processing protein 8

2

3

High-throughput

0.611

High

182224

PRKRA
Interferon-inducible double-stranded RNA-dependent protein kinase activator A

2

20

High-throughput

0.611

High

182227

SRP72
Signal recognition particle subunit SRP72

2

3

High-throughput

0.611

High

182239

ZNF22
Zinc finger protein 22

2

11

High-throughput

0.611

High

182249

RBM34
RNA-binding protein 34

2

12

High-throughput

0.611

High

182252

NOP2
28S rRNA

2

5

High-throughput

0.611

High

182263

RS3A
Small ribosomal subunit protein eS1

2

4

High-throughput

0.611

High

182269

RL32
Large ribosomal subunit protein eL32

2

1

High-throughput

0.611

High

182279

PURA
Transcriptional activator protein Pur-alpha

2

3

High-throughput

0.611

High

182283

ELAV2
ELAV-like protein 2

2

7

High-throughput

0.611

High

182301

TTF1
Transcription termination factor 1

2

5

High-throughput

0.611

High

182302

PUM3
Pumilio homolog 3

2

7

High-throughput

0.611

High

182305

IF16
Gamma-interferon-inducible protein 16

2

4

High-throughput

0.611

High

182306

KNOP1
Lysine-rich nucleolar protein 1

2

2

High-throughput

0.611

High

182310

GLYR1
Cytokine-like nuclear factor N-PAC

2

7

High-throughput

0.611

High

182316

LAR1B
La-related protein 1B

2

7

High-throughput

0.611

High

182319

CC137
Coiled-coil domain-containing protein 137

2

3

High-throughput

0.611

High

182323

ZCCHV
Zinc finger CCCH-type antiviral protein 1

2

8

High-throughput

0.611

High

182330

PAPD5
Terminal nucleotidyltransferase 4B

2

3

High-throughput

0.611

High

182336

BRX1
Ribosome biogenesis protein BRX1 homolog

2

11

High-throughput

0.611

High

182338

NOC3L
Nucleolar complex protein 3 homolog

2

7

High-throughput

0.611

High

182340

RENT1
Regulator of nonsense transcripts 1

2

4

High-throughput

0.611

High

182342

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

2

6

High-throughput

0.611

High

182348

POP1
Ribonucleases P/MRP protein subunit POP1

2

1

High-throughput

0.611

High

182351

EBP2
Probable rRNA-processing protein EBP2

2

3

High-throughput

0.611

High

182352

BUD13
BUD13 homolog

2

7

High-throughput

0.611

High

182367

NOL6
Nucleolar protein 6

2

3

High-throughput

0.611

High

182377

ZCHC3
Zinc finger CCHC domain-containing protein 3

2

4

High-throughput

0.611

High

182379

STAU2
Double-stranded RNA-binding protein Staufen homolog 2

2

20

High-throughput

0.611

High

182388

RLP24
Probable ribosome biogenesis protein RLP24

2

4

High-throughput

0.611

High

182394

RRP7A
Ribosomal RNA-processing protein 7 homolog A

2

2

High-throughput

0.611

High

182396

DCAF1
DDB1- and CUL4-associated factor 1

2

19

High-throughput

0.611

High

182233

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.584

High

182373

SSF1
Suppressor of SWI4 1 homolog

2

2

High-throughput

0.584

High

182390

RL26L
Ribosomal protein uL24-like

2

4

High-throughput

0.584

High

139436

PESC
Pescadillo homolog

1

4

High-throughput

0.575

High

182333

DDX55
ATP-dependent RNA helicase DDX55

1

20

High-throughput

0.575

High

182236

NPM
Nucleophosmin

2

8

High-throughput

0.571

High

182244

H1T
Histone H1t

2

11

High-throughput

0.558

High

182304

ZKSC8
Zinc finger protein with KRAB and SCAN domains 8

2

9

High-throughput

0.558

High

182308

LIN41
E3 ubiquitin-protein ligase TRIM71

2

17

High-throughput

0.558

High

182313

HP1B3
Heterochromatin protein 1-binding protein 3

2

3

High-throughput

0.558

High

182315

RSBN1
Lysine-specific demethylase 9

2

1

High-throughput

0.558

High

182317

ZN770
Zinc finger protein 770

2

5

High-throughput

0.558

High

182344

ZN668
Zinc finger protein 668

2

5

High-throughput

0.558

High

182345

ZN512
Zinc finger protein 512

2

7

High-throughput

0.558

High

182346

ZN317
Zinc finger protein 317

2

3

High-throughput

0.558

High

182349

ZN184
Zinc finger protein 184

2

1

High-throughput

0.558

High

182386

ZN629
Zinc finger protein 629

2

3

High-throughput

0.558

High

182389

ZN777
Zinc finger protein 777

2

7

High-throughput

0.558

High

182395

RRP15
RRP15-like protein

2

2

High-throughput

0.558

High

182397

ZFP37
Zinc finger protein 37 homolog

2

3

High-throughput

0.558

High

182320

TRI67
Tripartite motif-containing protein 67

1

15

High-throughput

0.553

High

182366

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.553

High

163859

NDC80
Kinetochore protein NDC80 homolog

1

16

High-throughput

0.536

High

182216

NKRF
NF-kappa-B-repressing factor

1

1

High-throughput

0.536

High

182217

NVL
Nuclear valosin-containing protein-like

1

6

High-throughput

0.536

High

182226

RL1D1
Ribosomal L1 domain-containing protein 1

1

10

High-throughput

0.536

High

182238

YBOX3
Y-box-binding protein 3

1

8

High-throughput

0.536

High

182251

KI67
Proliferation marker protein Ki-67

1

8

High-throughput

0.536

High

182267

RS6
Small ribosomal subunit protein eS6

1

3

High-throughput

0.536

High

182270

SUMO1
Small ubiquitin-related modifier 1

1

2

High-throughput

0.536

High

182274

RED1
Double-stranded RNA-specific editase 1

1

13

High-throughput

0.536

High

182280

SET
Protein SET

1

4

High-throughput

0.536

High

182285

SRSF5
Serine/arginine-rich splicing factor 5

1

15

High-throughput

0.536

High

182286

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.536

High

182321

MARK2
Serine/threonine-protein kinase MARK2

1

4

High-throughput

0.536

High

182334

CTCFL
Transcriptional repressor CTCFL

1

7

High-throughput

0.536

High

182339

CKAP2
Cytoskeleton-associated protein 2

1

1

High-throughput

0.536

High

182354

LLPH
Protein LLP homolog

1

1

High-throughput

0.536

High

182372

MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2

1

1

High-throughput

0.536

High

182391

NIP7
60S ribosome subunit biogenesis protein NIP7 homolog

1

1

High-throughput

0.536

High

182246

CALX
Calnexin

1

4

High-throughput

0.515

High

182261

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

182229

SYFM
Phenylalanine--tRNA ligase, mitochondrial

1

1

High-throughput

0.489

High

182262

RAP1B
Ras-related protein Rap-1b

1

8

High-throughput

0.489

High

182325

ZN677
Zinc finger protein 677

1

2

High-throughput

0.489

High

182329

ZBT44
Zinc finger and BTB domain-containing protein 44

1

9

High-throughput

0.489

High

182341

FGF13
Fibroblast growth factor 13

1

2

High-throughput

0.489

High

182358

TBB2B
Tubulin beta-2B chain

1

20

High-throughput

0.489

High

128623

MEN1
Menin

1

4

High-throughput

0.479

High

182220

PRC1
Protein regulator of cytokinesis 1

1

6

High-throughput

0.479

High

182230

NSA2
Ribosome biogenesis protein NSA2 homolog

1

3

High-throughput

0.479

High

182237

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

182241

NUCL
Nucleolin

1

6

High-throughput

0.479

High

182242

CSK22
Casein kinase II subunit alpha'

1

16

High-throughput

0.479

High

182243

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

5

High-throughput

0.479

High

182245

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

182247

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.479

High

182250

RL35
Large ribosomal subunit protein uL29

1

2

High-throughput

0.479

High

182254

SOX2
Transcription factor SOX-2

1

19

High-throughput

0.479

High

182255

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

7

High-throughput

0.479

High

182259

RBM5
RNA-binding protein 5

1

11

High-throughput

0.479

High

182260

FOXA1
Hepatocyte nuclear factor 3-alpha

1

3

High-throughput

0.479

High

182264

RL37A
Large ribosomal subunit protein eL43

1

3

High-throughput

0.479

High

182265

RS13
Small ribosomal subunit protein uS15

1

5

High-throughput

0.479

High

182268

RL10A
Large ribosomal subunit protein uL1

1

10

High-throughput

0.479

High

182278

TFAM
Transcription factor A, mitochondrial

1

16

High-throughput

0.479

High

182287

TIF1B
Transcription intermediary factor 1-beta

1

11

High-throughput

0.479

High

182288

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

182289

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.479

High

182291

EXOS2
Exosome complex component RRP4

1

5

High-throughput

0.479

High

182292

CDK13
Cyclin-dependent kinase 13

1

13

High-throughput

0.479

High

182294

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

6

High-throughput

0.479

High

182297

TNIP1
TNFAIP3-interacting protein 1

1

12

High-throughput

0.479

High

182303

TRBP2
RISC-loading complex subunit TARBP2

1

19

High-throughput

0.479

High

182312

RRP12
RRP12-like protein

1

2

High-throughput

0.479

High

182332

NGDN
Neuroguidin

1

4

High-throughput

0.479

High

182347

RING2
E3 ubiquitin-protein ligase RING2

1

18

High-throughput

0.479

High

182355

NOL10
Nucleolar protein 10

1

3

High-throughput

0.479

High

182359

UT14A
U3 small nucleolar RNA-associated protein 14 homolog A

1

5

High-throughput

0.479

High

182361

REPI1
DNA-binding protein REPIN1

1

5

High-throughput

0.479

High

182362

GTPB4
GTP-binding protein 4

1

9

High-throughput

0.479

High

182365

TSYL1
Testis-specific Y-encoded-like protein 1

1

4

High-throughput

0.479

High

182374

SAS10
Something about silencing protein 10

1

4

High-throughput

0.479

High

182376

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

2

High-throughput

0.479

High

182382

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

2

High-throughput

0.479

High

182383

AATF
Protein AATF

1

4

High-throughput

0.479

High

182387

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

182225

NPM3
Nucleoplasmin-3

1

8

High-throughput

0.445

High

182235

JUN
Transcription factor Jun

1

12

High-throughput

0.445

High

182240

HMGA1
High mobility group protein HMG-I/HMG-Y

1

1

High-throughput

0.445

High

182248

RL3
Large ribosomal subunit protein uL3

1

6

High-throughput

0.445

High

182253

RS10
Small ribosomal subunit protein eS10

1

6

High-throughput

0.445

High

182257

RL14
Large ribosomal subunit protein eL14

1

4

High-throughput

0.445

High

182272

SRPK2
SRSF protein kinase 2

1

20

High-throughput

0.445

High

182281

H11
Histone H1.1

1

10

High-throughput

0.445

High

182296

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

6

High-throughput

0.445

High

182307

TSR1
Pre-rRNA-processing protein TSR1 homolog

1

4

High-throughput

0.445

High

182318

CAVN1
Caveolae-associated protein 1

1

2

High-throughput

0.445

High

182357

MMTA2
Multiple myeloma tumor-associated protein 2

1

1

High-throughput

0.445

High

182392

YBOX2
Y-box-binding protein 2

1

8

High-throughput

0.445

High

182221

PRKN
E3 ubiquitin-protein ligase parkin

1

12

High-throughput

0.437

High

182223

OBSL1
Obscurin-like protein 1

1

7

High-throughput

0.437

High

182234

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

3

High-throughput

0.437

High

182258

JAK3
Tyrosine-protein kinase JAK3

1

9

High-throughput

0.437

High

182275

RT10
Small ribosomal subunit protein uS10m

1

1

High-throughput

0.437

High

182299

KIF14
Kinesin-like protein KIF14

1

11

High-throughput

0.437

High

182335

CERK1
Ceramide kinase

1

2

High-throughput

0.437

High

182337

ZN483
Zinc finger protein 483

1

3

High-throughput

0.437

High

182360

KIFC1
Kinesin-like protein KIFC1

1

4

High-throughput

0.437

High

182331

SRFB1
Serum response factor-binding protein 1

1

0

High-throughput

0.426

High

182353

PYM1
Partner of Y14 and mago

1

0

High-throughput

0.426

High

182370

EAF6
Chromatin modification-related protein MEAF6

1

0

High-throughput

0.426

High

182218

MAGB2
Melanoma-associated antigen B2

1

9

High-throughput

0.407

High

182327

ZN276
Zinc finger protein 276

1

10

High-throughput

0.407

High

182328

RNF10
E3 ubiquitin-protein ligase RNF10

1

2

High-throughput

0.407

High

158642

TYB4Y
Thymosin beta-4, Y-chromosomal

1

0

High-throughput

0.279

Low

169173

QCR10
Cytochrome b-c1 complex subunit 10

1

0

High-throughput

0.279

Low

182228

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

0

High-throughput

0.279

Low

182276

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.279

Low

182295

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

182309

KR197
Keratin-associated protein 19-7

1

0

High-throughput

0.279

Low

182311

GAG2E
G antigen 2E

1

0

High-throughput

0.279

Low

182314

CP141
Cilia- and flagella-associated protein 141

1

0

High-throughput

0.279

Low

182378

TM14B
Transmembrane protein 14B

1

0

High-throughput

0.279

Low

182324

SZRD1
SUZ RNA-binding domain-containing

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025