HitPredict

Interactor 1: SOX5 (P35711)
Transcription factor SOX-5
Gene: SOX5

Interactor 2: PRC2A (P48634)
Protein PRRC2A (HLA-B-associated transcript 2) (Large proline-rich protein BAT2) (Proline-rich and coiled-coil-containing protein 2A) (Protein G2)
Gene: PRRC2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35140242
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 763 Hs			1 2157
+	Hs
		727837 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		PRC2A_HUMAN (1-2157): 4.11e-162: 555: 100.00
+	Hs
		727832 SOX5_HUMAN (1-763): 0: 611: 100.00		NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40
+	Hs
		727830 SOX5_HUMAN (1-763): 0: 611: 100.00		PRC2C_HUMAN (33-1884): 4.13e-12: 74.4: 11.13
+	Hs
		152602 SOX5_HUMAN (1-763): 0: 611: 100.00		KMT2D_HUMAN (411-984): 1.99e-09: 65.4: 19.37
+	Hs
		727788 SOX5_HUMAN (1-763): 0: 611: 100.00		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Hs
		818122 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		PRC2B_HUMAN (1-2145): 2.51e-121: 430: 25.60
+	Hs
		727951 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		NCOR2_HUMAN (550-2096): 1.47e-20: 102: 10.40
+	Hs
		727947 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		PRC2C_HUMAN (33-1884): 4.13e-12: 74.4: 11.13
+	Hs
		727910 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Hs
		818819 SOX9_HUMAN (463-700): 7.73e-45: 170: 26.86		KMT2C_HUMAN (79-2077): 7.51e-50: 199: 10.05
+	Hs
		818266 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		KMT2C_HUMAN (79-2077): 7.51e-50: 199: 10.05
+	Hs
		807628 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		MAP1B_HUMAN (491-2148): 1.27e-36: 155: 8.83
+	Hs
		818226 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		ANKH1_HUMAN (88-992): 9.48e-35: 148: 14.15
+	Hs
		818382 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		MINT_HUMAN (338-2157): 4.08e-29: 130: 10.26
+	Hs
		160162 HGS_HUMAN (99-513): 1.79e-48: 185: 14.02		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Hs
		152611 SOX9_HUMAN (463-700): 7.73e-45: 170: 26.86		KMT2D_HUMAN (411-984): 1.99e-09: 65.4: 19.37
+	Hs
		818837 SOX9_HUMAN (463-700): 7.73e-45: 170: 26.86		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78
+	Hs
		817913 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		MAP1A_HUMAN (389-2155): 2.3e-14: 81.6: 8.60
+	Hs
		152610 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		KMT2D_HUMAN (411-984): 1.99e-09: 65.4: 19.37
+	Hs
		818373 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		CIC_HUMAN (8-701): 6.41e-09: 63.9: 8.78