HitPredict

Interactor 1: BDF1 (P35817)
Bromodomain-containing factor 1
Gene: BDF1

Interactor 2: SPP1 (Q03012)
COMPASS component SPP1 (Complex proteins associated with SET1 protein SPP1) (Set1C component SPP1) (Suppressor of PRP protein 1)
Gene: SPP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	22875988
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Bromodomain~PHD
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 686 Sc			1 353
+	Sc
		728686 BDF1_YEAST (1-671): 6.18e-147: 445: 100.00		YNG2_YEAST (12-74): 7.19e-11: 64: 33.33
+	Hs
		600258 TAF1_HUMAN (103-657): 6.62e-61: 223: 12.18		PHF8_HUMAN (22-205): 4.96e-40: 152: 21.39
+	Hs
		1342841 BRD7_HUMAN (14-550): 1.39e-59: 213: 14.46		PHF8_HUMAN (22-205): 4.96e-40: 152: 21.39
+	Sc
		733289 RSC4_YEAST (105-686): 4.92e-54: 198: 15.22		SET3_YEAST (4-140): 3.01e-27: 114: 19.05
+	Hs
		600164 TAF1_HUMAN (103-657): 6.62e-61: 223: 12.18		TAF3_HUMAN (27-69): 1.38e-14: 77.1: 41.86
+	Hs
		1356828 BRPF3_HUMAN (62-286): 9.58e-33: 137: 15.56		PHF8_HUMAN (22-205): 4.96e-40: 152: 21.39
+	Hs
		1067196 BRD3_HUMAN (306-466): 3.16e-26: 116: 23.60		PHF8_HUMAN (22-205): 4.96e-40: 152: 21.39
+	Hs
		1270830 CBP_HUMAN (249-418): 7.85e-37: 150: 25.73		ING1_HUMAN (9-95): 4.66e-22: 98.3: 28.89
+	Hs
		256383 BRD2_HUMAN (297-549): 3.19e-26: 116: 18.18		PHF2_HUMAN (22-203): 1.7e-31: 127: 19.29
+	Hs
		256411 BRD3_HUMAN (306-466): 3.16e-26: 116: 23.60		PHF2_HUMAN (22-203): 1.7e-31: 127: 19.29
+	Hs
		319380 BRD1_HUMAN (96-329): 1.26e-35: 146: 14.53		ING4_HUMAN (9-76): 3.75e-19: 87.5: 32.39
+	Hs
		1348038 BRPF3_HUMAN (62-286): 9.58e-33: 137: 15.56		ING3_HUMAN (10-79): 1.14e-18: 88.3: 35.62
+	Hs
		1356827 BRPF3_HUMAN (62-286): 9.58e-33: 137: 15.56		ING4_HUMAN (9-76): 3.75e-19: 87.5: 32.39
+	Hs
		1017300 BRD3_HUMAN (306-466): 3.16e-26: 116: 23.60		BPTF_HUMAN (11-126): 5.11e-22: 99.9: 22.22
+	Hs
		631413 BRD2_HUMAN (297-549): 3.19e-26: 116: 18.18		BPTF_HUMAN (11-126): 5.11e-22: 99.9: 22.22
+	Hs
		244354 BRD4_HUMAN (267-427): 1.9e-25: 114: 26.71		BPTF_HUMAN (11-126): 5.11e-22: 99.9: 22.22
+	Hs
		1067194 BRD3_HUMAN (306-466): 3.16e-26: 116: 23.60		ING4_HUMAN (9-76): 3.75e-19: 87.5: 32.39
+	Hs
		1066999 BRD3_HUMAN (306-466): 3.16e-26: 116: 23.60		TAF3_HUMAN (27-69): 1.38e-14: 77.1: 41.86
+	Hs
		631460 BRD2_HUMAN (297-549): 3.19e-26: 116: 18.18		TAF3_HUMAN (27-69): 1.38e-14: 77.1: 41.86
+	Hs
		244558 BRD4_HUMAN (267-427): 1.9e-25: 114: 26.71		TAF3_HUMAN (27-69): 1.38e-14: 77.1: 41.86