HitPredict

Interactor 1: BDF1 (P35817)
Bromodomain-containing factor 1
Gene: BDF1

Interactor 2: ESA1 (Q08649)
Histone acetyltransferase ESA1 (EC 2.3.1.48) (Protein 2-hydroxyisobutyryltransferase ESA1) (EC 2.3.1.-) (Protein acetyltransferase ESA1) (EC 2.3.1.-) (Protein crotonyltransferase ESA1) (EC 2.3.1.-)
Gene: ESA1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	21179020, 15353583
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006281 - DNA repair
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 686 Sc			1 445
+	Sc
		710434 BDF1_YEAST (1-671): 6.18e-147: 445: 100.00		SAS3_YEAST (91-439): 1.16e-131: 401: 34.53
+	Hs
		309660 TAF1_HUMAN (103-657): 6.62e-61: 223: 12.18		KAT7_HUMAN (50-434): 1.1e-178: 514: 39.55
+	Sc
		991242 BDF2_YEAST (17-331): 4.8e-28: 121: 16.35		ESA1_YEAST (1-445): 0: 608: 100.00
+	Hs
		309749 BRD7_HUMAN (14-550): 1.39e-59: 213: 14.46		KAT7_HUMAN (50-434): 1.1e-178: 514: 39.55
+	Hs
		309639 BRD1_HUMAN (96-329): 1.26e-35: 146: 14.53		KAT7_HUMAN (50-434): 1.1e-178: 514: 39.55
+	Hs
		309758 BRPF3_HUMAN (62-286): 9.58e-33: 137: 15.56		KAT7_HUMAN (50-434): 1.1e-178: 514: 39.55
+	Hs
		319284 BRD1_HUMAN (96-329): 1.26e-35: 146: 14.53		KAT6B_HUMAN (93-439): 6.53e-158: 493: 41.43
+	Hs
		1199175 PB1_HUMAN (91-664): 4.19e-38: 154: 11.97		KAT6A_HUMAN (92-439): 1.21e-154: 484: 42.74
+	Hs
		1270756 CBP_HUMAN (249-418): 7.85e-37: 150: 25.73		KAT6A_HUMAN (92-439): 1.21e-154: 484: 42.74
+	Hs
		1264463 BRPF3_HUMAN (62-286): 9.58e-33: 137: 15.56		KAT6B_HUMAN (93-439): 6.53e-158: 493: 41.43
+	Hs
		309662 BRD2_HUMAN (297-549): 3.19e-26: 116: 18.18		KAT7_HUMAN (50-434): 1.1e-178: 514: 39.55
+	Hs
		309702 BRD3_HUMAN (306-466): 3.16e-26: 116: 23.60		KAT7_HUMAN (50-434): 1.1e-178: 514: 39.55
+	Hs
		319291 BRD1_HUMAN (96-329): 1.26e-35: 146: 14.53		KAT6A_HUMAN (92-439): 1.21e-154: 484: 42.74
+	Hs
		243738 BRD4_HUMAN (267-427): 1.9e-25: 114: 26.71		KAT7_HUMAN (50-434): 1.1e-178: 514: 39.55
+	Hs
		1270980 BRPF3_HUMAN (62-286): 9.58e-33: 137: 15.56		KAT6A_HUMAN (92-439): 1.21e-154: 484: 42.74
+	Sc
		710449 RSC4_YEAST (105-686): 4.92e-54: 198: 15.22		SAS3_YEAST (91-439): 1.16e-131: 401: 34.53
+	Hs
		1270762 CBP_HUMAN (249-418): 7.85e-37: 150: 25.73		KAT5_HUMAN (17-165): 3.96e-19: 91.7: 27.27
+	Hs
		319294 BRD1_HUMAN (96-329): 1.26e-35: 146: 14.53		KAT5_HUMAN (17-165): 3.96e-19: 91.7: 27.27
+	Hs
		1273531 BRPF3_HUMAN (62-286): 9.58e-33: 137: 15.56		KAT5_HUMAN (17-165): 3.96e-19: 91.7: 27.27
+	Hs
		1067172 BRD3_HUMAN (306-466): 3.16e-26: 116: 23.60		MO4L1_HUMAN (20-180): 8.97e-13: 71.2: 11.50