HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28977666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 639 Hs			1 1912
+	Hs
		380612 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1059897 KRT84_HUMAN (5-589): 2.17e-100: 320: 44.20		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		409060 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1059714 K2C73_HUMAN (1-598): 8.9e-92: 296: 51.00		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		943630 KRT83_HUMAN (83-491): 2.11e-86: 280: 49.02		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		531571 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		380476 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		821658 K2C6C_HUMAN (5-510): 2.02e-81: 269: 61.61		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1059702 K2C1B_HUMAN (58-509): 2.24e-79: 264: 61.95		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		359491 K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		517753 K2C3_HUMAN (27-494): 2.18e-66: 230: 64.32		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		380602 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018708 KRT84_HUMAN (5-589): 2.17e-100: 320: 44.20		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		531559 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		380468 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		821652 K2C6C_HUMAN (5-510): 2.02e-81: 269: 61.61		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018554 K2C1B_HUMAN (58-509): 2.24e-79: 264: 61.95		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		359486 K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		729073 K22E_HUMAN (1-517): 4.22e-68: 235: 100.00		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		517749 K2C3_HUMAN (27-494): 2.18e-66: 230: 64.32		CHD3_HUMAN (23-1905): 0: 1595: 66.89