HitPredict

Interactor 1: K22E (P35908)
Keratin, type II cytoskeletal 2 epidermal (Cytokeratin-2e) (CK-2e) (Epithelial keratin-2e) (Keratin-2 epidermis) (Keratin-2e) (K2e) (Type-II keratin Kb2)
Gene: KRT2

Interactor 2: UBS3B (Q8TF42)
Ubiquitin-associated and SH3 domain-containing protein B (EC 3.1.3.48) (Cbl-interacting protein p70) (Suppressor of T-cell receptor signaling 1) (STS-1) (T-cell ubiquitin ligand 2) (TULA-2) (Tyrosine-protein phosphatase STS1/TULA2)
Gene: UBASH3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 639 Hs			1 649
+	Hs
		409176 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		380655 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		1205248 K2C73_HUMAN (1-598): 8.9e-92: 296: 51.00		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		531608 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		380504 K2C6B_HUMAN (5-510): 8.35e-82: 270: 61.22		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		1140440 K2C79_HUMAN (32-568): 4.69e-80: 264: 55.35		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		359518 K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22		UBS3B_HUMAN (1-649): 0: 1066: 100.00
+	Hs
		409046 K2C8_HUMAN (150-535): 1.29e-143: 427: 59.33		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		444533 K2C7_HUMAN (86-542): 4.82e-131: 395: 52.62		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		380590 K2C1_HUMAN (143-509): 1.63e-112: 353: 71.94		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924679 K2C73_HUMAN (1-598): 8.9e-92: 296: 51.00		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924470 KRT85_HUMAN (5-491): 4.47e-87: 282: 45.59		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924576 KRT81_HUMAN (72-491): 2.86e-87: 282: 48.46		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		213936 KRT86_HUMAN (72-557): 8.74e-87: 281: 44.35		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		924469 KRT83_HUMAN (83-491): 2.11e-86: 280: 49.02		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		531551 K2C5_HUMAN (1-494): 7.49e-82: 271: 61.48		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		359480 K2C6A_HUMAN (5-510): 8.33e-78: 259: 61.22		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Hs
		729063 K22E_HUMAN (1-517): 4.22e-68: 235: 100.00		GRB2_HUMAN (156-319): 1.37e-45: 163: 21.56
+	Mm
		1141145 Q8BIS2_MOUSE (16-503): 1.61e-66: 229: 53.69		GRB2_MOUSE (156-319): 3.38e-45: 161: 21.56
+	Hs
		729089 K22E_HUMAN (1-517): 4.22e-68: 235: 100.00		LASP1_HUMAN (254-315): 1.29e-12: 70.2: 30.65