HitPredict

Interactor 1: VGFR3 (P35916)
Vascular endothelial growth factor receptor 3 (VEGFR-3) (EC 2.7.10.1) (Fms-like tyrosine kinase 4) (FLT-4) (Tyrosine-protein kinase receptor FLT4)
Gene: FLT4

Interactor 2: SMC1A (Q14683)
Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)
Gene: SMC1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1363 Hs			1 1233
+	Hs
		311490 VGFR3_HUMAN (1-1363): 0: 982: 100.00		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		572635 VGFR1_HUMAN (19-1342): 0: 828: 38.63		SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00
+	Hs
		729386 VGFR3_HUMAN (1-1363): 0: 982: 100.00		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00
+	Hs
		311473 VGFR1_HUMAN (19-1342): 0: 828: 38.63		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		738210 FLT3_HUMAN (837-1217): 1.41e-97: 338: 45.98		SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00
+	Hs
		311491 FLT3_HUMAN (837-1217): 1.41e-97: 338: 45.98		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		665375 EPHA3_HUMAN (386-1200): 1.47e-152: 489: 14.15		MYH9_HUMAN (49-760): 1.43e-25: 117: 11.62
+	Hs
		738293 FLT3_HUMAN (837-1217): 1.41e-97: 338: 45.98		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00
+	Hs
		609288 FGFR3_HUMAN (310-670): 4.9e-27: 121: 13.53		SMC1A_HUMAN (1-1233): 1.94e-128: 427: 100.00
+	Hs
		311477 FGFR3_HUMAN (310-670): 4.9e-27: 121: 13.53		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57
+	Hs
		609617 FGFR3_HUMAN (310-670): 4.9e-27: 121: 13.53		SMC3_HUMAN (3-1229): 1.52e-70: 260: 16.00
+	Hs
		311465 FGFR1_HUMAN (2-160): 6.17e-14: 78.9: 11.93		SMC2_HUMAN (3-1214): 1.55e-77: 281: 17.57